Chlorine in PDB 6bsg: Structure of Hiv-1 Rt Complexed with Rna/Dna Hybrid in An Rna Hydrolysis-Off Mode

The structure of Structure of Hiv-1 Rt Complexed with Rna/Dna Hybrid in An Rna Hydrolysis-Off Mode, PDB code: 6bsg was solved by L.Tian, M.Kim, W.Yang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.51 / 2.44
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	162.040, 162.040, 129.180, 90.00, 90.00, 120.00
R / Rfree (%)	19.1 / 22.4

The structure of Structure of Hiv-1 Rt Complexed with Rna/Dna Hybrid in An Rna Hydrolysis-Off Mode also contains other interesting chemical elements:

Fluorine	(F)	3 atoms
Calcium	(Ca)	2 atoms

The binding sites of Chlorine atom in the Structure of Hiv-1 Rt Complexed with Rna/Dna Hybrid in An Rna Hydrolysis-Off Mode (pdb code 6bsg). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Hiv-1 Rt Complexed with Rna/Dna Hybrid in An Rna Hydrolysis-Off Mode, PDB code: 6bsg:

Chlorine binding site 1 out of 1 in the Structure of Hiv-1 Rt Complexed with Rna/Dna Hybrid in An Rna Hydrolysis-Off Mode


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Hiv-1 Rt Complexed with Rna/Dna Hybrid in An Rna Hydrolysis-Off Mode within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl601 b:63.4 occ:1.00 CL A:EFZ601 0.0 63.4 1.0 C4 A:EFZ601 1.7 54.3 1.0 C3 A:EFZ601 2.5 53.4 1.0 C5 A:EFZ601 2.6 55.7 1.0 CB A:LEU234 3.6 47.4 1.0 O A:HIS235 3.7 55.3 1.0 CG2 A:VAL106 3.8 61.3 1.0 CG1 A:VAL106 3.8 56.8 1.0 C2 A:EFZ601 3.8 56.2 1.0 C6 A:EFZ601 3.9 58.2 1.0 CD2 A:PHE227 3.9 55.0 1.0 O A:LEU234 3.9 56.6 1.0 CB A:VAL106 3.9 61.4 1.0 C A:HIS235 4.1 56.8 1.0 C A:LEU234 4.1 58.4 1.0 CE2 A:PHE227 4.4 54.2 1.0 OH A:TYR318 4.4 50.7 1.0 CA A:LEU234 4.5 46.8 1.0 N A:HIS235 4.5 52.9 1.0 N A:PRO236 4.5 61.8 1.0 CD1 A:LEU234 4.5 52.3 1.0 C1 A:EFZ601 4.6 50.2 1.0 CA A:HIS235 4.7 53.1 1.0 CA A:PRO236 4.7 58.7 1.0 CG A:LEU234 4.7 56.1 1.0 F3 A:EFZ601 4.9 66.5 1.0

L.Tian, M.S.Kim, H.Li, J.Wang, W.Yang. Structure of Hiv-1 Reverse Transcriptase Cleaving Rna in An Rna/Dna Hybrid. Proc. Natl. Acad. Sci. V. 115 507 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 29295939
DOI: 10.1073/PNAS.1719746115