Atomistry » Chlorine » PDB 6c7i-6cdq » 6c9f
Atomistry »
  Chlorine »
    PDB 6c7i-6cdq »
      6c9f »

Chlorine in PDB 6c9f: Amp-Activated Protein Kinase Bound to Pharmacological Activator R734

Enzymatic activity of Amp-Activated Protein Kinase Bound to Pharmacological Activator R734

All present enzymatic activity of Amp-Activated Protein Kinase Bound to Pharmacological Activator R734:
2.7.11.1; 2.7.11.26; 2.7.11.27; 2.7.11.31;

Protein crystallography data

The structure of Amp-Activated Protein Kinase Bound to Pharmacological Activator R734, PDB code: 6c9f was solved by Y.Yan, X.E.Zhou, S.Novick, S.J.Shaw, Y.Li, Y.Hitoshi, J.S.Brunzelle, P.R.Griffin, H.E.Xu, K.Melcher, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 49.67 / 2.92
Space group P 61 2 2
Cell size a, b, c (Å), α, β, γ (°) 123.289, 123.289, 406.594, 90.00, 90.00, 120.00
R / Rfree (%) 22.8 / 24.5

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Amp-Activated Protein Kinase Bound to Pharmacological Activator R734 (pdb code 6c9f). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Amp-Activated Protein Kinase Bound to Pharmacological Activator R734, PDB code: 6c9f:

Chlorine binding site 1 out of 1 in 6c9f

Go back to Chlorine Binding Sites List in 6c9f
Chlorine binding site 1 out of 1 in the Amp-Activated Protein Kinase Bound to Pharmacological Activator R734


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Amp-Activated Protein Kinase Bound to Pharmacological Activator R734 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl601

b:39.4
occ:1.00
CL1 A:R34601 0.0 39.4 1.0
C10 A:R34601 1.8 24.5 1.0
C11 A:R34601 2.7 26.4 1.0
C7 A:R34601 2.8 24.0 1.0
C2 A:R34601 3.1 23.4 1.0
C3 A:R34601 3.2 23.3 1.0
CZ A:PHE92 3.6 39.2 1.0
CG1 B:VAL113 3.7 31.5 1.0
CE2 A:PHE92 3.8 34.3 1.0
CG1 B:VAL81 3.9 33.9 1.0
C12 A:R34601 4.0 32.9 1.0
C14 A:R34601 4.1 23.1 1.0
CD1 B:ILE115 4.1 43.1 1.0
CG2 B:VAL81 4.1 35.9 1.0
C21 A:R34601 4.2 22.9 1.0
C4 A:R34601 4.3 23.6 1.0
CG1 B:ILE115 4.4 40.9 1.0
CG2 B:VAL113 4.6 33.5 1.0
C13 A:R34601 4.6 29.9 1.0
CG1 A:VAL13 4.6 39.9 1.0
CD1 A:ILE48 4.6 25.1 1.0
CB B:VAL113 4.6 32.4 1.0
CB B:VAL81 4.7 33.1 1.0
CG2 A:ILE48 4.8 40.6 1.0
CE1 A:PHE92 4.8 37.6 1.0
CD1 A:LEU20 4.9 20.4 1.0

Reference:

Y.Yan, X.E.Zhou, S.J.Novick, S.J.Shaw, Y.Li, J.S.Brunzelle, Y.Hitoshi, P.R.Griffin, H.E.Xu, K.Melcher. Structures of Amp-Activated Protein Kinase Bound to Novel Pharmacological Activators in Phosphorylated, Non-Phosphorylated, and Nucleotide-Free States. J. Biol. Chem. V. 294 953 2019.
ISSN: ESSN 1083-351X
PubMed: 30478170
DOI: 10.1074/JBC.RA118.004883
Page generated: Sat Jul 12 12:18:32 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy