Chlorine in PDB 6caj: Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B From Homo Sapiens

The binding sites of Chlorine atom in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B From Homo Sapiens (pdb code 6caj). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B From Homo Sapiens, PDB code: 6caj:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B From Homo Sapiens


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B From Homo Sapiens within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl401 b:52.6 occ:0.50 CL1 C:C7B401 0.0 52.6 0.5 CL2 C:C7B401 0.4 52.6 0.5 C29 C:C7B401 1.8 52.6 0.5 C30 C:C7B401 2.0 52.6 0.5 C27 C:C7B401 2.7 52.6 0.5 CG2 D:VAL225 2.7 1.0 1.0 C25 C:C7B401 2.8 52.6 0.5 C26 C:C7B401 2.9 52.6 0.5 C28 C:C7B401 3.1 52.6 0.5 CE D:MET217 3.2 1.0 1.0 CD2 E:LEU485 4.0 1.0 1.0 CB D:VAL225 4.0 1.0 1.0 C23 C:C7B401 4.0 52.6 0.5 C21 C:C7B401 4.1 52.6 0.5 CD1 D:ILE190 4.1 1.0 1.0 C22 C:C7B401 4.2 52.6 0.5 C24 C:C7B401 4.3 52.6 0.5 CG2 D:THR215 4.5 1.0 1.0 C19 C:C7B401 4.6 52.6 0.5 CG1 D:ILE190 4.6 1.0 1.0 SD D:MET217 4.7 1.0 1.0 CG1 E:VAL177 4.8 1.0 1.0 C20 C:C7B401 4.8 52.6 0.5 CG1 D:VAL225 4.8 1.0 1.0 CE2 E:PHE180 4.9 1.0 1.0 CE1 E:PHE452 5.0 1.0 1.0

Chlorine binding site 2 out of 4 in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B From Homo Sapiens


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B From Homo Sapiens within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl401 b:52.6 occ:0.50 CL1 C:C7B401 0.0 52.6 0.5 CL2 C:C7B401 0.4 52.6 0.5 C29 C:C7B401 1.8 52.6 0.5 C30 C:C7B401 2.0 52.6 0.5 C27 C:C7B401 2.7 52.6 0.5 CG2 C:VAL225 2.7 1.0 1.0 C25 C:C7B401 2.8 52.6 0.5 C26 C:C7B401 2.9 52.6 0.5 C28 C:C7B401 3.1 52.6 0.5 CE C:MET217 3.1 1.0 1.0 CD2 F:LEU485 3.9 1.0 1.0 C23 C:C7B401 4.0 52.6 0.5 CB C:VAL225 4.0 1.0 1.0 C21 C:C7B401 4.1 52.6 0.5 CD1 C:ILE190 4.1 1.0 1.0 C22 C:C7B401 4.2 52.6 0.5 C24 C:C7B401 4.3 52.6 0.5 CG2 C:THR215 4.5 1.0 1.0 C19 C:C7B401 4.6 52.6 0.5 CG1 C:ILE190 4.6 1.0 1.0 SD C:MET217 4.7 1.0 1.0 CG1 F:VAL177 4.8 1.0 1.0 C20 C:C7B401 4.8 52.6 0.5 CG1 C:VAL225 4.8 1.0 1.0 CE2 F:PHE180 4.9 1.0 1.0

Chlorine binding site 3 out of 4 in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B From Homo Sapiens


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B From Homo Sapiens within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl401 b:52.6 occ:0.50 CL2 C:C7B401 0.0 52.6 0.5 CL1 C:C7B401 0.4 52.6 0.5 C29 C:C7B401 1.6 52.6 0.5 C30 C:C7B401 1.8 52.6 0.5 C27 C:C7B401 2.4 52.6 0.5 C25 C:C7B401 2.7 52.6 0.5 C28 C:C7B401 2.7 52.6 0.5 C26 C:C7B401 2.8 52.6 0.5 CG2 C:VAL225 3.1 1.0 1.0 CE C:MET217 3.4 1.0 1.0 C23 C:C7B401 3.7 52.6 0.5 C21 C:C7B401 3.9 52.6 0.5 CD2 F:LEU485 3.9 1.0 1.0 C24 C:C7B401 4.0 52.6 0.5 C22 C:C7B401 4.0 52.6 0.5 CD1 C:ILE190 4.3 1.0 1.0 CG2 C:THR215 4.3 1.0 1.0 C19 C:C7B401 4.3 52.6 0.5 CB C:VAL225 4.4 1.0 1.0 CG1 F:VAL177 4.4 1.0 1.0 C20 C:C7B401 4.6 52.6 0.5 CG1 C:ILE190 4.6 1.0 1.0 CE2 F:PHE180 4.9 1.0 1.0 CD1 F:LEU179 4.9 1.0 1.0 CB C:THR215 5.0 1.0 1.0

Chlorine binding site 4 out of 4 in the Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B From Homo Sapiens


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Electron Cryo-Microscopy of the Eukaryotic Translation Initiation Factor 2B From Homo Sapiens within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl401 b:52.6 occ:0.50 CL2 C:C7B401 0.0 52.6 0.5 CL1 C:C7B401 0.4 52.6 0.5 C29 C:C7B401 1.6 52.6 0.5 C30 C:C7B401 1.8 52.6 0.5 C27 C:C7B401 2.4 52.6 0.5 C25 C:C7B401 2.7 52.6 0.5 C28 C:C7B401 2.7 52.6 0.5 C26 C:C7B401 2.8 52.6 0.5 CG2 D:VAL225 3.1 1.0 1.0 CE D:MET217 3.4 1.0 1.0 C23 C:C7B401 3.7 52.6 0.5 C21 C:C7B401 3.9 52.6 0.5 CD2 E:LEU485 3.9 1.0 1.0 C24 C:C7B401 4.0 52.6 0.5 C22 C:C7B401 4.0 52.6 0.5 CD1 D:ILE190 4.2 1.0 1.0 C19 C:C7B401 4.3 52.6 0.5 CG2 D:THR215 4.3 1.0 1.0 CB D:VAL225 4.4 1.0 1.0 CG1 E:VAL177 4.4 1.0 1.0 C20 C:C7B401 4.6 52.6 0.5 CG1 D:ILE190 4.6 1.0 1.0 CE2 E:PHE180 4.9 1.0 1.0 CD1 E:LEU179 4.9 1.0 1.0

J.C.Tsai, L.E.Miller-Vedam, A.A.Anand, P.Jaishankar, H.C.Nguyen, A.R.Renslo, A.Frost, P.Walter. Structure of the Nucleotide Exchange Factor EIF2B Reveals Mechanism of Memory-Enhancing Molecule. Science V. 359 2018.
ISSN: ESSN 1095-9203
PubMed: 29599213
DOI: 10.1126/SCIENCE.AAQ0939