Chlorine in PDB 6cbx: Crystal Structure of Human Set and Mynd Domain Containing Protein 2 with MTF1497

All present enzymatic activity of Crystal Structure of Human Set and Mynd Domain Containing Protein 2 with MTF1497:
2.1.1.43;

The structure of Crystal Structure of Human Set and Mynd Domain Containing Protein 2 with MTF1497, PDB code: 6cbx was solved by H.Zeng, A.Dong, A.Hutchinson, A.Seitova, J.Tatlock, R.Kumpf, A.Owen, A.Taylor, A.Casimiro-Garcia, C.Bountra, C.H.Arrowsmith, A.M.Edwards, P.J.Brown, H.Wu, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.94
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	58.020, 117.031, 64.444, 90.00, 92.54, 90.00
R / Rfree (%)	18 / 22.3

The structure of Crystal Structure of Human Set and Mynd Domain Containing Protein 2 with MTF1497 also contains other interesting chemical elements:

Zinc

(Zn)

6 atoms

The binding sites of Chlorine atom in the Crystal Structure of Human Set and Mynd Domain Containing Protein 2 with MTF1497 (pdb code 6cbx). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human Set and Mynd Domain Containing Protein 2 with MTF1497, PDB code: 6cbx:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Human Set and Mynd Domain Containing Protein 2 with MTF1497


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Set and Mynd Domain Containing Protein 2 with MTF1497 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1005 b:34.8 occ:1.00 N A:ASP242 3.2 23.9 1.0 O A:HOH1277 3.2 33.1 1.0 O A:HOH1174 3.4 25.9 1.0 CB A:ILE241 3.6 20.9 0.5 CB A:ASP242 3.7 25.0 1.0 CB A:ILE241 3.7 23.2 0.5 CG A:ARG253 3.7 33.6 1.0 CG2 A:ILE241 3.8 20.9 0.5 CA A:ILE241 3.8 21.7 0.5 CA A:ILE241 3.8 22.7 0.5 CG2 A:ILE241 4.0 23.3 0.5 C A:ILE241 4.0 22.4 1.0 CB A:ARG253 4.0 28.9 1.0 CA A:ASP242 4.0 24.4 1.0 CD A:ARG253 4.1 34.8 1.0 NE A:ARG253 4.5 39.0 1.0 O A:HOH1262 4.5 39.6 1.0 O A:ASP242 4.8 23.9 1.0 C A:ASP242 4.9 23.4 1.0 O A:HOH1120 5.0 29.1 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Human Set and Mynd Domain Containing Protein 2 with MTF1497


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human Set and Mynd Domain Containing Protein 2 with MTF1497 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1005 b:41.9 occ:1.00 N B:ASP242 3.1 27.0 1.0 O B:HOH1146 3.2 33.9 1.0 CB B:ILE241 3.6 22.8 1.0 CG B:ARG253 3.6 42.1 1.0 CB B:ASP242 3.7 26.7 1.0 CA B:ILE241 3.7 24.0 1.0 CG2 B:ILE241 3.8 24.7 1.0 C B:ILE241 3.9 25.7 1.0 CA B:ASP242 4.0 25.7 1.0 CB B:ARG253 4.3 34.1 1.0 CD B:ARG253 4.4 46.6 1.0 O B:ASP242 4.8 25.0 1.0 C B:ASP242 4.9 26.4 1.0 CG1 B:ILE241 4.9 23.5 1.0

H.Zeng, A.Dong, A.Hutchinson, A.Seitova, J.Tatlock, R.Kumpf, A.Owen, A.Taylor, A.Casimiro-Garcia, C.Bountra, C.H.Arrowsmith, A.M.Edwards, P.J.Brown, H.Wu, Structural Genomics Consortium (Sgc). Crystal Structure of Human Set and Mynd Domain Containing Protein 2 with MTF1497 To Be Published.