Chlorine in PDB 6dbc: Second Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue

The structure of Second Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue, PDB code: 6dbc was solved by S.W.White, M.Yun, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.72 / 1.05
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	52.394, 72.186, 31.975, 90.00, 90.00, 90.00
R / Rfree (%)	12.8 / 13.2

The binding sites of Chlorine atom in the Second Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue (pdb code 6dbc). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Second Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue, PDB code: 6dbc:

Chlorine binding site 1 out of 1 in the Second Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Second Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl508 b:15.2 occ:1.00 CL2 A:G3J508 0.0 15.2 1.0 C05 A:G3J508 1.8 12.9 1.0 C08 A:G3J508 2.7 10.3 1.0 C04 A:G3J508 2.7 13.1 1.0 N09 A:G3J508 3.0 10.1 1.0 O A:HOH735 3.4 29.1 1.0 C2 A:EDO505 3.6 28.3 1.0 O A:HOH724 3.6 36.5 1.0 C2 A:EDO507 3.7 37.9 1.0 O A:HOH738 3.7 24.1 1.0 CE1 A:HIS433 3.7 13.4 1.0 C1 A:EDO507 4.0 38.0 1.0 NE2 A:HIS433 4.0 15.0 1.0 C07 A:G3J508 4.0 10.6 1.0 C03 A:G3J508 4.0 12.9 1.0 O2 A:EDO507 4.1 37.4 1.0 O2 A:EDO505 4.4 29.2 1.0 C10 A:G3J508 4.4 8.7 1.0 C06 A:G3J508 4.5 11.7 1.0 C1 A:EDO505 4.7 27.2 1.0 ND1 A:HIS433 5.0 11.8 1.0

S.W.White, M.Yun. Second Bromodomain of Human BRD2 with A Tetrahydroquinoline Analogue To Be Published.