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Atomistry » Chlorine » PDB 6el4-6erc » 6eo8 » |
Chlorine in PDB 6eo8: Crystal Structure of Thrombin in Complex with A Novel Glucose- Conjugated Potent InhibitorEnzymatic activity of Crystal Structure of Thrombin in Complex with A Novel Glucose- Conjugated Potent Inhibitor
All present enzymatic activity of Crystal Structure of Thrombin in Complex with A Novel Glucose- Conjugated Potent Inhibitor:
3.4.21.5; Protein crystallography data
The structure of Crystal Structure of Thrombin in Complex with A Novel Glucose- Conjugated Potent Inhibitor, PDB code: 6eo8
was solved by
B.D.Belviso,
R.Caliandro,
B.M.Aresta,
M.De Candia,
C.D.Altomare,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Thrombin in Complex with A Novel Glucose- Conjugated Potent Inhibitor
(pdb code 6eo8). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Thrombin in Complex with A Novel Glucose- Conjugated Potent Inhibitor, PDB code: 6eo8: Chlorine binding site 1 out of 1 in 6eo8Go back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure of Thrombin in Complex with A Novel Glucose- Conjugated Potent Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
B.D.Belviso,
R.Caliandro,
M.De Candia,
G.Zaetta,
G.Lopopolo,
F.Incampo,
M.Colucci,
C.D.Altomare.
How A Beta-D-Glucoside Side Chain Enhances Binding Affinity to Thrombin of Inhibitors Bearing 2-Chlorothiophene As P1 Moiety: Crystallography, Fragment Deconstruction Study, and Evaluation of Antithrombotic Properties. J. Med. Chem. V. 57 8563 2014.
Page generated: Sat Jul 27 22:30:09 2024
ISSN: ISSN 1520-4804 PubMed: 25268757 DOI: 10.1021/JM5010754 |
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