Chlorine in PDB 6flb: 3H5 Fab Bound to Ediii of Denv 2 Xtal Form 2

The structure of 3H5 Fab Bound to Ediii of Denv 2 Xtal Form 2, PDB code: 6flb was solved by A.Flanagan, M.Renner, J.M.Grimes, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	21.29 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	38.492, 131.573, 139.442, 90.00, 90.00, 90.00
R / Rfree (%)	17.6 / 21.8

The binding sites of Chlorine atom in the 3H5 Fab Bound to Ediii of Denv 2 Xtal Form 2 (pdb code 6flb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the 3H5 Fab Bound to Ediii of Denv 2 Xtal Form 2, PDB code: 6flb:

Chlorine binding site 1 out of 1 in the 3H5 Fab Bound to Ediii of Denv 2 Xtal Form 2


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of 3H5 Fab Bound to Ediii of Denv 2 Xtal Form 2 within 5.0Å range: probe atom residue distance (Å) B Occ L:Cl301 b:28.8 occ:1.00 NE2 H:GLN35 3.2 23.9 1.0 ND2 L:ASN95 3.2 19.5 1.0 NE2 L:GLN93 3.4 32.4 1.0 CE H:MET104 3.8 26.4 1.0 CD2 L:PHE100 3.8 27.3 1.0 CG H:MET104 3.8 28.1 1.0 CE2 L:PHE100 3.8 28.6 1.0 OE1 L:GLN93 3.9 36.4 1.0 CD H:LYS99 3.9 25.4 1.0 CA H:ALA103 3.9 24.9 1.0 CE H:LYS99 3.9 25.2 1.0 N H:MET104 4.0 25.6 1.0 CG H:LYS99 4.0 27.4 1.0 CD L:GLN93 4.1 39.3 1.0 C H:ALA103 4.1 27.8 1.0 CD H:GLN35 4.2 35.5 1.0 CG L:ASN95 4.2 28.8 1.0 CB L:ASN95 4.3 23.3 1.0 OE1 H:GLN35 4.4 30.2 1.0 SD H:MET104 4.4 30.5 1.0 OH L:TYR40 4.5 28.4 1.0 O H:PHE102 4.6 26.2 1.0 CB H:ALA103 4.7 26.1 1.0 CB H:MET104 4.7 27.1 1.0 CA H:MET104 4.8 25.7 1.0 CB H:LYS99 4.8 24.9 1.0 CG L:PHE100 4.9 26.5 1.0 CZ L:PHE100 4.9 27.7 1.0 O H:ALA103 4.9 25.8 1.0 N H:ALA103 4.9 24.7 1.0

M.Renner, A.Flanagan, W.Dejnirattisai, C.Puttikhunt, W.Kasinrerk, P.Supasa, W.Wongwiwat, K.Chawansuntati, T.Duangchinda, A.Cowper, C.M.Midgley, P.Malasit, J.T.Huiskonen, J.Mongkolsapaya, G.R.Screaton, J.M.Grimes. Characterization of A Potent and Highly Unusual Minimally Enhancing Antibody Directed Against Dengue Virus. Nat. Immunol. V. 19 1248 2018.
ISSN: ESSN 1529-2916
PubMed: 30323338
DOI: 10.1038/S41590-018-0227-7