Atomistry » Chlorine » PDB 6fla-6frx » 6fq3
Atomistry »
  Chlorine »
    PDB 6fla-6frx »
      6fq3 »

Chlorine in PDB 6fq3: Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna

Enzymatic activity of Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna

All present enzymatic activity of Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna:
2.3.2.27;

Protein crystallography data

The structure of Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna, PDB code: 6fq3 was solved by P.Kumari, F.Aeschimann, D.Gaidatzis, J.J.Keusch, P.Ghosh, A.Neagu, K.Pachulska-Wieczorek, J.M.Bujnicki, H.Gut, H.Grosshans, R.Ciosk, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.64 / 1.90
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 101.850, 101.850, 109.890, 90.00, 90.00, 120.00
R / Rfree (%) 15.8 / 18

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna (pdb code 6fq3). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 8 binding sites of Chlorine where determined in the Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna, PDB code: 6fq3:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Chlorine binding site 1 out of 8 in 6fq3

Go back to Chlorine Binding Sites List in 6fq3
Chlorine binding site 1 out of 8 in the Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl901

b:73.5
occ:0.70
 O A:HOH1147 3.2 61.5 1.0
NZ A:LYS649 4.4 62.3 1.0
CA A:GLY650 4.4 48.5 1.0
CG2 A:THR651 4.9 48.4 1.0

Chlorine binding site 2 out of 8 in 6fq3

Go back to Chlorine Binding Sites List in 6fq3
Chlorine binding site 2 out of 8 in the Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl902

b:94.7
occ:1.00
 NE2 A:HIS678 3.0 43.2 1.0
O A:HOH1169 3.7 79.9 1.0
CD2 A:HIS678 3.9 44.2 1.0
CE1 A:HIS678 3.9 45.2 1.0
CE2 A:TRP700 4.1 52.0 1.0
O A:HOH1117 4.2 66.8 1.0
NE1 A:TRP700 4.3 56.1 1.0
CZ2 A:TRP700 4.3 54.5 1.0
CD2 A:TRP700 4.4 45.5 1.0
CD1 A:TRP700 4.6 53.2 1.0
CG A:TRP700 4.7 44.2 1.0
CH2 A:TRP700 4.7 51.9 1.0
CE3 A:TRP700 4.8 44.7 1.0
CZ3 A:TRP700 5.0 44.5 1.0

Chlorine binding site 3 out of 8 in 6fq3

Go back to Chlorine Binding Sites List in 6fq3
Chlorine binding site 3 out of 8 in the Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl903

b:0.8
occ:1.00
 O A:HOH1179 3.4 68.4 1.0
O A:HOH1062 3.6 63.6 1.0
CE1 A:HIS702 4.1 55.2 1.0
O A:LYS701 4.2 42.2 1.0
NE2 A:HIS702 4.2 52.2 1.0
ND1 A:HIS702 4.2 52.1 1.0
C A:LYS701 4.3 43.3 1.0
CB A:LYS701 4.3 50.1 1.0
CD2 A:HIS702 4.4 52.7 1.0
N A:HIS702 4.4 40.3 1.0
CG A:HIS702 4.4 49.4 1.0
CA A:HIS702 4.6 39.7 1.0
CL A:CL907 4.6 87.3 1.0
CA A:LYS701 5.0 42.8 1.0

Chlorine binding site 4 out of 8 in 6fq3

Go back to Chlorine Binding Sites List in 6fq3
Chlorine binding site 4 out of 8 in the Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl904

b:0.9
occ:1.00
 OE2 A:GLU555 3.5 0.4 1.0
O A:HOH1180 3.6 72.3 1.0
CD A:GLU555 4.0 0.6 1.0
ND2 A:ASN819 4.0 59.6 1.0
O A:HOH1056 4.1 53.0 1.0
CG A:ARG564 4.2 52.6 1.0
N4 B:C6 4.3 95.6 1.0
OD1 A:ASN819 4.4 60.7 1.0
OE1 A:GLU555 4.5 0.7 1.0
CG A:GLU555 4.6 89.7 1.0
SG A:CYS563 4.6 67.8 1.0
CG A:ASN819 4.6 61.0 1.0
CD A:ARG564 4.7 54.4 1.0
O A:HOH1027 4.8 67.0 1.0
C4 B:C6 4.9 90.0 1.0

Chlorine binding site 5 out of 8 in 6fq3

Go back to Chlorine Binding Sites List in 6fq3
Chlorine binding site 5 out of 8 in the Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl905

b:99.3
occ:1.00
 N A:ASN653 3.5 51.4 1.0
O A:HOH1099 3.8 63.0 1.0
CG A:ASN653 3.8 56.1 1.0
CB A:LYS652 3.8 48.6 1.0
ND2 A:ASN653 3.8 58.0 1.0
CA A:LYS652 3.9 49.9 1.0
OD1 A:ASN653 4.0 55.2 1.0
CG A:LYS652 4.1 53.8 1.0
C A:LYS652 4.2 50.2 1.0
CB A:ASN653 4.2 56.8 1.0
CA A:ASN653 4.5 52.8 1.0
O A:HOH1101 5.0 73.7 1.0

Chlorine binding site 6 out of 8 in 6fq3

Go back to Chlorine Binding Sites List in 6fq3
Chlorine binding site 6 out of 8 in the Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl906

b:93.0
occ:1.00
 O A:GLY694 3.6 52.3 1.0
CE1 A:PHE695 3.7 48.2 1.0
O A:HOH1153 3.8 72.5 1.0
CE1 A:TYR693 3.9 51.5 1.0
CD1 A:PHE695 4.0 47.2 1.0
CZ A:PHE695 4.2 44.1 1.0
CZ A:TYR693 4.3 50.6 1.0
CD1 A:TYR693 4.4 51.1 1.0
C A:GLY694 4.4 51.6 1.0
OH A:TYR693 4.5 50.9 1.0
O A:HOH1007 4.6 62.8 1.0
CG A:PHE695 4.6 45.4 1.0
CE2 A:PHE695 4.8 44.5 1.0
N A:GLY694 4.8 47.8 1.0
O A:GLN735 4.9 63.7 1.0
CD2 A:PHE695 5.0 45.4 1.0
O A:HOH1026 5.0 60.7 1.0

Chlorine binding site 7 out of 8 in 6fq3

Go back to Chlorine Binding Sites List in 6fq3
Chlorine binding site 7 out of 8 in the Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl907

b:87.3
occ:1.00
 O A:HOH1156 2.6 63.5 1.0
NE A:ARG726 3.6 42.1 1.0
NH2 A:ARG726 4.0 42.4 1.0
CZ A:ARG726 4.2 42.1 1.0
CD A:ARG726 4.4 43.1 1.0
CL A:CL903 4.6 0.8 1.0
ND2 A:ASN724 4.6 44.8 1.0
CD2 A:HIS702 4.7 52.7 1.0
O A:HIS702 4.7 45.2 1.0
CA A:HIS702 4.8 39.7 1.0
O A:HOH1049 4.8 44.4 1.0
CG A:ASN724 4.9 44.2 1.0

Chlorine binding site 8 out of 8 in 6fq3

Go back to Chlorine Binding Sites List in 6fq3
Chlorine binding site 8 out of 8 in the Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Crystal Structure of Danio Rerio LIN41 Filamin-Nhl Domains in Complex with Lin-29A 5'Utr 13MER Rna within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl101

b:0.4
occ:1.00
 N7 B:A9 3.2 46.9 1.0
O A:HOH1097 3.4 70.7 1.0
O A:HOH1113 3.6 72.1 1.0
N6 B:A9 3.7 48.4 1.0
NH2 A:ARG676 3.8 59.3 0.5
C5 B:A9 4.1 45.3 1.0
C8 B:A9 4.2 45.9 1.0
C6 B:A9 4.3 48.5 1.0
O B:HOH251 4.5 69.1 1.0
O B:HOH233 4.6 63.0 1.0
O B:HOH252 4.7 72.2 1.0
O B:HOH216 4.8 53.9 1.0
CZ A:ARG676 4.9 58.4 0.5
N7 B:A8 5.0 51.9 1.0

Reference:

P.Kumari, F.Aeschimann, D.Gaidatzis, J.J.Keusch, P.Ghosh, A.Neagu, K.Pachulska-Wieczorek, J.M.Bujnicki, H.Gut, H.Grosshans, R.Ciosk. Evolutionary Plasticity of the Nhl Domain Underlies Distinct Solutions to Rna Recognition. Nat Commun V. 9 1549 2018.
ISSN: ESSN 2041-1723
PubMed: 29674686
DOI: 10.1038/S41467-018-03920-7
Page generated: Sat Jul 12 14:10:43 2025

Last articles

Fe in 6CIQ
Fe in 6CDK
Fe in 6CII
Fe in 6CFW
Fe in 6CIF
Fe in 6CIE
Fe in 6CID
Fe in 6CIC
Fe in 6CHI
Fe in 6CI0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy