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Atomistry » Chlorine » PDB 6g8m-6ggn » 6gcx | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 6g8m-6ggn » 6gcx » |
Chlorine in PDB 6gcx: Focal Adhesion Kinase Catalytic Domain in Complex with Irreversible InhibitorEnzymatic activity of Focal Adhesion Kinase Catalytic Domain in Complex with Irreversible Inhibitor
All present enzymatic activity of Focal Adhesion Kinase Catalytic Domain in Complex with Irreversible Inhibitor:
2.7.10.2; Protein crystallography data
The structure of Focal Adhesion Kinase Catalytic Domain in Complex with Irreversible Inhibitor, PDB code: 6gcx
was solved by
E.Yen-Pon,
B.Li,
M.Acebron-Garcia De Eulate,
C.Tomkiewicz-Raulet,
J.Dawson,
D.Lietha,
M.C.Frame,
X.Coumoul,
C.Garbay,
M.Etheve-Quelquejeu,
H.Chen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Focal Adhesion Kinase Catalytic Domain in Complex with Irreversible Inhibitor
(pdb code 6gcx). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Focal Adhesion Kinase Catalytic Domain in Complex with Irreversible Inhibitor, PDB code: 6gcx: Chlorine binding site 1 out of 1 in 6gcxGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Focal Adhesion Kinase Catalytic Domain in Complex with Irreversible Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
E.Yen-Pon,
B.Li,
M.Acebron-Garcia-De-Eulate,
C.Tomkiewicz-Raulet,
J.Dawson,
D.Lietha,
M.C.Frame,
X.Coumoul,
C.Garbay,
M.Etheve-Quelquejeu,
H.Chen.
Structure-Based Design, Synthesis, and Characterization of the First Irreversible Inhibitor of Focal Adhesion Kinase. Acs Chem.Biol. V. 13 2067 2018.
Page generated: Sat Jul 12 14:30:00 2025
ISSN: ESSN 1554-8937 PubMed: 29897729 DOI: 10.1021/ACSCHEMBIO.8B00250 |
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