Chlorine in PDB 6gr4: Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112R

The structure of Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112R, PDB code: 6gr4 was solved by G.Tassone, C.Pozzi, S.Mangani, M.Botta, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	55.31 / 1.50
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	66.179, 89.818, 100.369, 90.00, 90.00, 90.00
R / Rfree (%)	16.5 / 19.3

The structure of Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112R also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Chlorine atom in the Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112R (pdb code 6gr4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112R, PDB code: 6gr4:

Chlorine binding site 1 out of 1 in the Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112R


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112R within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl302 b:22.5 occ:0.70 O A:HOH635 2.7 39.7 1.0 O A:HOH611 3.0 21.5 1.0 OG A:SER113 3.1 23.2 1.0 N A:SER113 3.2 19.5 1.0 CB A:SER113 3.5 21.7 1.0 CB A:ILE110 3.6 18.8 1.0 O A:ILE110 3.6 15.3 1.0 C A:ILE110 3.7 16.6 1.0 CA A:ILE110 3.9 15.7 1.0 CA A:SER113 3.9 20.6 1.0 CB A:ARG112 4.0 23.2 1.0 N A:ARG112 4.0 18.5 1.0 NH1 A:ARG112 4.2 37.6 0.5 C A:ARG112 4.2 19.9 1.0 CA A:ARG112 4.3 19.8 1.0 CG2 A:ILE110 4.3 20.1 1.0 N A:ALA111 4.4 16.6 1.0 O A:HOH535 4.5 39.0 1.0 CG1 A:ILE110 4.6 19.6 1.0 C A:ALA111 4.8 17.2 1.0 CD1 A:ILE110 4.9 21.0 1.0 CZ A:ARG112 4.9 35.1 0.5

G.Tassone, S.Mangani, M.Botta, C.Pozzi. Probing the Role of ARG97 in Heat Shock Protein 90 N-Terminal Domain From the Parasite Leishmania Braziliensis Through Site-Directed Mutagenesis on the Human Counterpart. Biochim Biophys Acta V.1866 1190 2018PROTEINS Proteom.
ISSN: ISSN 1878-1454
PubMed: 30248409
DOI: 10.1016/J.BBAPAP.2018.09.005