Chlorine in PDB 6h5t: Intersectin SH3A Short Isoform

The structure of Intersectin SH3A Short Isoform, PDB code: 6h5t was solved by J.H.Driller, F.Gerth, C.Freund, M.C.Wahl, B.Loll, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.69 / 1.69
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	86.792, 86.792, 141.768, 90.00, 90.00, 90.00
R / Rfree (%)	17.6 / 19.1

The structure of Intersectin SH3A Short Isoform also contains other interesting chemical elements:

Zinc

(Zn)

3 atoms

The binding sites of Chlorine atom in the Intersectin SH3A Short Isoform (pdb code 6h5t). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Intersectin SH3A Short Isoform, PDB code: 6h5t:

Chlorine binding site 1 out of 1 in the Intersectin SH3A Short Isoform


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Intersectin SH3A Short Isoform within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl902 b:31.5 occ:0.43 O A:HOH1016 3.0 18.6 0.3 N A:GLU776 3.2 27.3 1.0 O A:HOH1046 3.6 28.8 0.7 CA A:GLY775 3.7 28.3 1.0 C A:GLY775 3.9 30.4 1.0 CA A:GLU776 4.1 22.8 1.0 O A:GLU776 4.2 32.3 1.0 CB A:GLU776 4.2 30.8 1.0 C A:GLU776 4.4 29.5 1.0 O A:HOH1014 4.4 48.3 1.0 O A:HOH1018 4.5 33.7 1.0 CG A:GLU776 4.7 32.2 1.0 O A:HOH1070 4.8 41.6 1.0 OE2 A:GLU776 4.9 38.7 1.0

F.Gerth, M.Japel, J.Sticht, B.Kuropka, X.J.Schmitt, J.H.Driller, B.Loll, M.C.Wahl, K.Pagel, V.Haucke, C.Freund. Exon Inclusion Modulates Conformational Plasticity and Autoinhibition of the Intersectin 1 SH3A Domain. Structure V. 27 977 2019.
ISSN: ISSN 0969-2126
PubMed: 31031201
DOI: 10.1016/J.STR.2019.03.020