Chlorine in PDB 6hb1: Structure of HGH1, Crystal Form I

The structure of Structure of HGH1, Crystal Form I, PDB code: 6hb1 was solved by L.Moenkemeyer, C.L.Klaips, D.Balchin, R.Koerner, F.U.Hartl, A.Bracher, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.30 / 2.33
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	80.207, 86.427, 88.368, 118.48, 105.80, 99.15
R / Rfree (%)	17.7 / 22.6

The binding sites of Chlorine atom in the Structure of HGH1, Crystal Form I (pdb code 6hb1). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Structure of HGH1, Crystal Form I, PDB code: 6hb1:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Structure of HGH1, Crystal Form I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of HGH1, Crystal Form I within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:0.3 occ:1.00 H A:VAL226 2.6 37.8 1.0 HD21 D:ASN26 2.6 48.4 1.0 HG23 A:VAL226 2.9 36.4 1.0 HA A:ALA224 2.9 62.4 1.0 H A:LYS225 3.0 34.3 1.0 O A:HOH572 3.1 53.0 1.0 HB A:VAL226 3.3 51.4 1.0 N A:LYS225 3.3 28.6 1.0 N A:VAL226 3.4 31.5 1.0 ND2 D:ASN26 3.4 40.4 1.0 HG23 D:ILE22 3.4 49.0 1.0 HB3 A:LYS225 3.6 51.6 1.0 CG2 A:VAL226 3.6 30.3 1.0 CA A:ALA224 3.7 52.0 1.0 C A:ALA224 3.8 51.6 1.0 HG21 A:VAL226 3.8 36.4 1.0 CB A:VAL226 3.8 42.8 1.0 HD22 A:ASN181 3.9 56.2 1.0 OD1 D:ASN26 3.9 49.3 1.0 HD22 D:ASN26 4.0 48.4 1.0 CG D:ASN26 4.1 41.2 1.0 HB1 A:ALA224 4.1 60.2 1.0 CA A:LYS225 4.2 45.5 1.0 CG2 D:ILE22 4.2 40.8 1.0 HG21 D:ILE22 4.2 49.0 1.0 CA A:VAL226 4.2 38.2 1.0 C A:LYS225 4.3 47.2 1.0 ND2 A:ASN181 4.3 46.9 1.0 CB A:LYS225 4.3 43.0 1.0 HD21 A:ASN181 4.4 56.2 1.0 HG22 D:ILE22 4.4 49.0 1.0 HG22 A:VAL226 4.4 36.4 1.0 H A:ARG227 4.4 41.7 1.0 CB A:ALA224 4.5 50.2 1.0 HB2 A:LYS225 4.6 51.6 1.0 O A:ALA224 4.7 29.9 1.0 O A:ASP223 4.7 50.3 1.0 HB2 A:ALA224 4.8 60.2 1.0 N A:ALA224 4.8 41.3 1.0 HA A:VAL226 4.9 45.8 1.0 HB3 A:ASN181 4.9 37.6 1.0

Chlorine binding site 2 out of 3 in the Structure of HGH1, Crystal Form I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of HGH1, Crystal Form I within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl401 b:0.3 occ:1.00 HD21 B:ASN26 2.4 53.4 1.0 H C:VAL226 2.6 44.5 1.0 HG23 C:VAL226 2.9 37.5 1.0 HA C:ALA224 3.0 46.8 1.0 H C:LYS225 3.1 42.1 1.0 HG23 B:ILE22 3.2 54.6 1.0 ND2 B:ASN26 3.2 44.5 1.0 HB C:VAL226 3.3 37.3 1.0 O B:HOH448 3.3 42.9 1.0 N C:LYS225 3.5 35.1 1.0 N C:VAL226 3.5 37.1 1.0 CG2 C:VAL226 3.6 31.2 1.0 HB3 C:LYS225 3.7 59.1 1.0 CA C:ALA224 3.8 39.0 1.0 HG21 C:VAL226 3.8 37.5 1.0 OD1 B:ASN26 3.8 45.4 1.0 HD22 B:ASN26 3.8 53.4 1.0 C C:ALA224 3.8 37.8 1.0 CB C:VAL226 3.8 31.1 1.0 HD22 C:ASN181 3.9 55.2 1.0 CG B:ASN26 3.9 62.7 1.0 CG2 B:ILE22 4.0 45.5 1.0 HG21 B:ILE22 4.0 54.6 1.0 HB1 C:ALA224 4.2 69.6 1.0 HG22 B:ILE22 4.2 54.6 1.0 CA C:LYS225 4.3 50.0 1.0 CA C:VAL226 4.3 46.1 1.0 ND2 C:ASN181 4.3 46.0 1.0 C C:LYS225 4.4 40.9 1.0 CB C:LYS225 4.4 49.3 1.0 HG22 C:VAL226 4.5 37.5 1.0 H C:ARG227 4.5 47.9 1.0 HD21 C:ASN181 4.5 55.2 1.0 CB C:ALA224 4.5 58.0 1.0 HB2 C:LYS225 4.7 59.1 1.0 O C:ALA224 4.7 32.1 1.0 O C:ASP223 4.7 53.9 1.0 HB3 C:ASN181 4.8 39.1 1.0 HG12 B:ILE22 4.8 68.5 1.0 HB2 C:ALA224 4.8 69.6 1.0 N C:ALA224 4.8 55.7 1.0 HA C:VAL226 4.9 55.3 1.0

Chlorine binding site 3 out of 3 in the Structure of HGH1, Crystal Form I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of HGH1, Crystal Form I within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl401 b:36.2 occ:1.00 HD21 D:ASN83 2.4 55.0 1.0 HE2 D:LYS79 2.9 69.4 1.0 ND2 D:ASN83 3.2 45.8 1.0 HZ3 D:LYS79 3.4 74.6 1.0 HZ1 D:LYS79 3.5 74.6 1.0 HG3 D:LYS79 3.6 50.1 1.0 HD22 D:ASN83 3.6 55.0 1.0 CE D:LYS79 3.7 57.8 1.0 NZ D:LYS79 3.7 62.1 1.0 HG2 D:LYS79 3.9 50.1 1.0 HD23 D:LEU80 4.0 48.6 1.0 CG D:LYS79 4.1 41.8 1.0 CG D:ASN83 4.2 52.0 1.0 OD1 D:ASN83 4.3 42.8 1.0 HE3 D:LYS79 4.3 69.4 1.0 HD21 D:LEU80 4.4 48.6 1.0 CD D:LYS79 4.5 61.7 1.0 HZ2 D:LYS79 4.6 74.6 1.0 CD2 D:LEU80 4.6 40.5 1.0 HD22 D:LEU80 4.9 48.6 1.0 HD2 D:LYS79 5.0 74.1 1.0

L.Monkemeyer, C.L.Klaips, D.Balchin, R.Korner, F.U.Hartl, A.Bracher. Chaperone Function of HGH1 in the Biogenesis of Eukaryotic Elongation Factor 2. Mol.Cell V. 74 88 2019.
ISSN: ISSN 1097-2765
PubMed: 30876804
DOI: 10.1016/J.MOLCEL.2019.01.034