Chlorine in PDB 6hon: Drosophila NOT4 Cbm Peptide Bound to Human CAF40

The structure of Drosophila NOT4 Cbm Peptide Bound to Human CAF40, PDB code: 6hon was solved by T.Raisch, E.Izaurralde, O.Weichenrieder, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.25 / 2.20
Space group	I 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	85.630, 90.320, 196.990, 90.00, 90.00, 90.00
R / Rfree (%)	19.3 / 23

The structure of Drosophila NOT4 Cbm Peptide Bound to Human CAF40 also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Chlorine atom in the Drosophila NOT4 Cbm Peptide Bound to Human CAF40 (pdb code 6hon). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Drosophila NOT4 Cbm Peptide Bound to Human CAF40, PDB code: 6hon:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Drosophila NOT4 Cbm Peptide Bound to Human CAF40


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Drosophila NOT4 Cbm Peptide Bound to Human CAF40 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl302 b:0.1 occ:1.00 OG A:SER175 3.5 80.9 1.0 N A:LEU177 3.5 70.4 1.0 CG A:LEU177 3.6 74.2 1.0 CB A:SER175 3.6 73.6 1.0 N A:GLU176 3.8 73.7 1.0 CB A:LEU177 3.8 67.8 1.0 O A:HOH426 3.9 79.3 1.0 CD1 A:LEU177 4.0 74.0 1.0 CB A:GLU176 4.3 78.1 1.0 CA A:LEU177 4.3 68.5 1.0 CA A:GLU176 4.3 74.1 1.0 C A:SER175 4.3 75.6 1.0 C A:GLU176 4.4 75.0 1.0 CA A:SER175 4.5 71.7 1.0 CD2 A:LEU177 4.8 77.0 1.0

Chlorine binding site 2 out of 2 in the Drosophila NOT4 Cbm Peptide Bound to Human CAF40


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Drosophila NOT4 Cbm Peptide Bound to Human CAF40 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl901 b:0.6 occ:1.00 N B:GLY817 3.2 96.3 1.0 N B:ASP814 3.3 0.2 1.0 N B:LEU816 3.4 0.3 1.0 OD1 B:ASP815 3.6 0.8 1.0 CB B:LEU816 3.6 99.4 1.0 CA B:ASP814 3.6 0.4 1.0 N B:ASP815 3.8 0.1 1.0 C B:ASP814 3.8 0.9 1.0 CA B:LEU816 3.8 0.3 1.0 C B:LEU816 4.0 0.1 1.0 O B:PHE818 4.1 78.9 1.0 CA B:GLY817 4.1 94.9 1.0 N B:PHE818 4.2 84.5 1.0 C B:ASP815 4.4 0.9 1.0 C B:GLY817 4.6 93.0 1.0 O B:ASP814 4.6 0.7 1.0 CA B:ASP815 4.6 0.7 1.0 CG B:ASP815 4.6 0.0 1.0 NZ A:LYS148 4.8 1.0 1.0 C B:PHE818 4.8 79.9 1.0 CG B:LEU816 4.9 0.5 1.0

C.Keskeny, T.Raisch, A.Sgromo, C.Igreja, D.Bhandari, O.Weichenrieder, E.Izaurralde. A Conserved CAF40-Binding Motif in Metazoan NOT4 Mediates Association with the CCR4-Not Complex. Genes Dev. V. 33 236 2019.
ISSN: ISSN 1549-5477
PubMed: 30692204
DOI: 10.1101/GAD.320952.118