Atomistry » Chlorine » PDB 6hsd-6hvw » 6htm
Atomistry »
  Chlorine »
    PDB 6hsd-6hvw »
      6htm »

Chlorine in PDB 6htm: X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin

Protein crystallography data

The structure of X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin, PDB code: 6htm was solved by P.Amara, J.M.Mouesca, M.Bella, C.Saragaglia, S.Gambarelli, Y.Nicolet, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.05 / 1.70
Space group P 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 94.530, 47.140, 113.900, 90.00, 108.90, 90.00
R / Rfree (%) 16.2 / 18.9

Other elements in 6htm:

The structure of X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin also contains other interesting chemical elements:

Zinc (Zn) 1 atom
Bromine (Br) 6 atoms
Iron (Fe) 8 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin (pdb code 6htm). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 7 binding sites of Chlorine where determined in the X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin, PDB code: 6htm:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7;

Chlorine binding site 1 out of 7 in 6htm

Go back to Chlorine Binding Sites List in 6htm
Chlorine binding site 1 out of 7 in the X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl2510

b:31.9
occ:1.00
 O A:HOH2757 2.8 31.4 0.5
O A:HOH2735 2.8 38.5 1.0
O A:HOH2748 3.0 26.0 1.0
OG A:SER281 3.2 26.1 1.0
O A:HOH2937 3.2 36.0 0.5
CB A:SER281 3.4 26.5 1.0
N1 A:TSS2501 3.4 33.6 0.5
CG2 A:THR321 3.7 23.5 1.0
CE2 A:PHE202 3.9 23.9 1.0
CG1 A:VAL319 3.9 26.9 1.0
CZ A:PHE202 3.9 25.8 1.0
NH1 A:ARG323 3.9 24.3 1.0
CA A:TSS2501 4.0 33.6 0.5
CB A:VAL319 4.2 24.8 1.0
CD A:PRO283 4.3 26.3 1.0
CA A:SER281 4.4 26.6 1.0
CB A:PRO283 4.5 25.4 1.0
O A:VAL319 4.6 26.6 1.0
CG A:PRO283 4.6 25.2 1.0
CZ A:ARG323 4.7 26.1 1.0
NH2 A:ARG323 4.9 28.8 1.0
N A:PRO283 4.9 26.8 1.0
O A:HOH2758 4.9 36.8 0.8
CE1 A:PHE202 5.0 23.5 1.0

Chlorine binding site 2 out of 7 in 6htm

Go back to Chlorine Binding Sites List in 6htm
Chlorine binding site 2 out of 7 in the X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl2511

b:35.2
occ:0.25
 CL A:CL2511 0.0 35.2 0.2
CD2 A:TSS2501 0.5 35.5 0.5
CE3 A:TSS2501 1.3 33.8 0.5
CE2 A:TSS2501 1.3 34.5 0.5
CG A:TSS2501 1.7 35.2 0.5
CZ3 A:TSS2501 2.1 34.4 0.5
CZ2 A:TSS2501 2.1 34.4 0.5
CL A:CL2511 2.2 33.8 0.2
NE1 A:TSS2501 2.3 34.5 0.5
CH2 A:TSS2501 2.4 34.8 0.5
CD1 A:TSS2501 2.5 35.7 0.5
O A:HOH2747 2.8 35.3 0.5
CB A:TSS2501 2.8 34.4 0.5
O A:HOH2758 2.9 36.8 0.8
NH1 A:ARG323 3.3 24.3 1.0
O A:HOH2816 3.5 34.9 0.5
O A:HOH2955 3.6 35.5 0.5
CA A:TSS2501 3.7 33.6 0.5
O A:HOH2757 3.7 31.4 0.5
CZ A:ARG323 4.0 26.1 1.0
CG A:PRO88 4.1 20.1 1.0
CB A:THR321 4.1 23.9 1.0
NH2 A:ARG323 4.1 28.8 1.0
CG2 A:THR321 4.2 23.5 1.0
OG1 A:THR321 4.3 23.6 1.0
N1 A:TSS2501 4.4 33.6 0.5
CB A:PRO88 4.5 18.7 1.0
CZ A:PHE364 4.8 32.8 1.0
CD A:PRO88 4.9 19.1 1.0
O A:SER340 4.9 25.1 1.0
NE A:ARG323 4.9 24.9 1.0

Chlorine binding site 3 out of 7 in 6htm

Go back to Chlorine Binding Sites List in 6htm
Chlorine binding site 3 out of 7 in the X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl2511

b:33.8
occ:0.25
 CL A:CL2511 0.0 33.8 0.2
CZ2 A:TSS2501 0.3 34.4 0.5
CE2 A:TSS2501 1.2 34.5 0.5
CH2 A:TSS2501 1.7 34.8 0.5
NE1 A:TSS2501 2.2 34.5 0.5
CL A:CL2511 2.2 35.2 0.2
CD2 A:TSS2501 2.4 35.5 0.5
O A:HOH2816 2.6 34.9 0.5
CZ3 A:TSS2501 2.7 34.4 0.5
CE3 A:TSS2501 3.0 33.8 0.5
O A:SER340 3.2 25.1 1.0
CD1 A:TSS2501 3.3 35.7 0.5
CG A:TSS2501 3.4 35.2 0.5
OG1 A:THR322 3.5 26.9 1.0
CB A:THR321 3.6 23.9 1.0
O A:HOH2758 3.6 36.8 0.8
CG A:PRO88 3.7 20.1 1.0
O A:GLY342 3.9 27.8 1.0
N A:GLY342 3.9 25.6 1.0
N A:THR322 4.0 22.8 1.0
CD A:PRO88 4.1 19.1 1.0
C A:GLY342 4.2 23.8 1.0
C A:PRO341 4.2 25.6 1.0
C A:SER340 4.2 23.0 1.0
OG1 A:THR321 4.2 23.6 1.0
CG2 A:THR321 4.3 23.5 1.0
CA A:GLY342 4.3 24.9 1.0
OG A:SER340 4.4 24.3 1.0
CA A:PRO341 4.5 22.8 1.0
CA A:THR321 4.5 23.2 1.0
CB A:THR322 4.7 25.1 1.0
O A:PRO341 4.7 25.6 1.0
C A:THR321 4.7 23.6 1.0
N A:PRO341 4.8 22.4 1.0
CB A:TSS2501 4.8 34.4 0.5
NH1 A:ARG323 4.8 24.3 1.0
CA A:THR322 4.8 22.6 1.0
CB A:PRO88 4.8 18.7 1.0
O A:HOH2747 4.8 35.3 0.5
N A:ARG323 4.9 23.8 1.0
CB A:SER340 4.9 22.2 1.0
N A:SER343 4.9 21.3 1.0

Chlorine binding site 4 out of 7 in 6htm

Go back to Chlorine Binding Sites List in 6htm
Chlorine binding site 4 out of 7 in the X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl512

b:24.6
occ:1.00
 N1 B:TSS502 2.9 37.9 0.3
O B:HOH715 3.0 26.2 1.0
O B:HOH887 3.2 35.3 0.8
OG B:SER281 3.2 18.1 1.0
O B:HOH693 3.4 36.2 1.0
CB B:SER281 3.4 16.6 1.0
O B:HOH1025 3.5 39.5 0.8
CG2 B:THR321 3.6 19.9 1.0
CA B:TSS502 3.8 36.2 0.3
CZ B:PHE202 3.9 19.2 1.0
CG1 B:VAL319 3.9 19.4 1.0
CE2 B:PHE202 3.9 19.0 1.0
NH1 B:ARG323 4.1 22.5 1.0
CB B:VAL319 4.2 20.1 1.0
CD B:PRO283 4.3 17.8 1.0
CA B:SER281 4.5 17.0 1.0
CB B:PRO283 4.5 20.8 1.0
O B:VAL319 4.5 20.9 1.0
CG B:PRO283 4.6 19.7 1.0
O B:HOH828 4.8 23.5 0.5
CZ B:ARG323 4.8 23.2 1.0
N B:PRO283 5.0 19.1 1.0
CB B:THR321 5.0 20.4 1.0
NH2 B:ARG323 5.0 23.8 1.0

Chlorine binding site 5 out of 7 in 6htm

Go back to Chlorine Binding Sites List in 6htm
Chlorine binding site 5 out of 7 in the X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl513

b:24.2
occ:0.25
 CL B:CL513 0.0 24.2 0.2
CD2 B:TSS502 0.6 24.4 0.3
CE3 B:TSS502 1.2 24.4 0.3
CE2 B:TSS502 1.3 24.1 0.3
CG B:TSS502 1.8 26.1 0.3
CL B:CL513 1.9 24.2 0.2
CZ3 B:TSS502 1.9 25.0 0.3
CZ2 B:TSS502 2.0 24.2 0.3
CH2 B:TSS502 2.3 24.9 0.3
NE1 B:TSS502 2.3 23.9 0.3
CD1 B:TSS502 2.6 24.0 0.3
O B:HOH802 2.7 32.5 0.8
O B:HOH828 3.0 23.5 0.5
CB B:TSS502 3.0 32.3 0.3
NH1 B:ARG323 3.2 22.5 1.0
O B:HOH887 3.6 35.3 0.8
CA B:TSS502 3.7 36.2 0.3
O B:HOH756 3.8 26.4 0.5
CZ B:ARG323 3.9 23.2 1.0
CG B:PRO88 3.9 20.0 1.0
CB B:THR321 4.0 20.4 1.0
NH2 B:ARG323 4.0 23.8 1.0
CG2 B:THR321 4.1 19.9 1.0
N1 B:TSS502 4.3 37.9 0.3
OG1 B:THR321 4.3 18.8 1.0
CB B:PRO88 4.5 18.0 1.0
O B:SER340 4.6 21.2 1.0
CZ B:PHE364 4.6 25.9 1.0
CD B:PRO88 4.8 18.6 1.0
OG B:SER340 4.9 21.1 1.0
NE B:ARG323 5.0 18.1 1.0

Chlorine binding site 6 out of 7 in 6htm

Go back to Chlorine Binding Sites List in 6htm
Chlorine binding site 6 out of 7 in the X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl513

b:24.2
occ:0.25
 CL B:CL513 0.0 24.2 0.2
CZ2 B:TSS502 0.5 24.2 0.3
CE2 B:TSS502 0.9 24.1 0.3
CH2 B:TSS502 1.8 24.9 0.3
CL B:CL513 1.9 24.2 0.2
NE1 B:TSS502 1.9 23.9 0.3
CD2 B:TSS502 2.1 24.4 0.3
CZ3 B:TSS502 2.6 25.0 0.3
CE3 B:TSS502 2.7 24.4 0.3
CD1 B:TSS502 3.0 24.0 0.3
O B:SER340 3.0 21.2 1.0
CG B:TSS502 3.0 26.1 0.3
O B:HOH756 3.2 26.4 0.5
O B:HOH828 3.4 23.5 0.5
CB B:THR321 3.5 20.4 1.0
CG B:PRO88 3.6 20.0 1.0
OG1 B:THR322 3.8 22.5 1.0
CD B:PRO88 3.9 18.6 1.0
C B:SER340 4.0 17.9 1.0
CG2 B:THR321 4.0 19.9 1.0
OG B:SER340 4.1 21.1 1.0
N B:GLY342 4.1 20.6 1.0
N B:THR322 4.1 18.1 1.0
OG1 B:THR321 4.2 18.8 1.0
O B:GLY342 4.3 23.4 1.0
C B:PRO341 4.3 21.8 1.0
O B:HOH802 4.4 32.5 0.8
NH1 B:ARG323 4.4 22.5 1.0
C B:GLY342 4.5 19.4 1.0
CA B:THR321 4.5 19.6 1.0
CA B:GLY342 4.5 21.2 1.0
CB B:TSS502 4.5 32.3 0.3
CB B:SER340 4.6 18.4 1.0
CA B:PRO341 4.6 21.7 1.0
CB B:PRO88 4.6 18.0 1.0
N B:PRO341 4.7 17.0 1.0
O B:PRO341 4.8 20.7 1.0
C B:THR321 4.9 18.0 1.0
CA B:SER340 5.0 18.2 1.0

Chlorine binding site 7 out of 7 in 6htm

Go back to Chlorine Binding Sites List in 6htm
Chlorine binding site 7 out of 7 in the X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of X-Ray Structure of the Tryptophan Lyase Nosl in Complex with Bound Tryptamin within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl514

b:48.2
occ:0.70
 O B:HOH771 1.8 46.1 0.3
ZN B:ZN515 2.2 31.6 0.7
NE2 B:HIS130 3.2 29.0 1.0
OE1 B:GLU126 3.4 38.5 1.0
OE2 B:GLU126 3.6 39.3 1.0
CD2 B:LEU167 3.9 27.2 1.0
CD B:GLU126 3.9 34.4 1.0
CE1 B:HIS130 3.9 29.6 1.0
O B:HOH968 4.2 56.9 1.0
CD2 B:HIS130 4.3 24.9 1.0
CD1 B:TYR129 4.4 21.9 1.0
O B:LEU167 4.4 28.0 1.0
CE1 B:TYR129 4.5 25.2 1.0
CG B:TYR129 4.7 19.1 1.0
CZ B:TYR129 4.9 26.1 1.0
CB B:LEU167 4.9 20.1 1.0
CG B:LEU167 5.0 25.3 1.0

Reference:

P.Amara, J.M.Mouesca, M.Bella, L.Martin, C.Saragaglia, S.Gambarelli, Y.Nicolet. Radical S-Adenosyl-L-Methionine Tryptophan Lyase (Nosl): How the Protein Controls the Carboxyl Radical •CO2-Migration. J.Am.Chem.Soc. V. 140 16661 2018.
ISSN: ESSN 1520-5126
PubMed: 30418774
DOI: 10.1021/JACS.8B09142
Page generated: Sun Jul 28 01:09:32 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy