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Atomistry » Chlorine » PDB 6mr5-6n3v » 6n3o | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 6mr5-6n3v » 6n3o » |
Chlorine in PDB 6n3o: Identification of Novel, Potent and Selective GCN2 Inhibitors As First-in-Class Anti-Tumor AgentsEnzymatic activity of Identification of Novel, Potent and Selective GCN2 Inhibitors As First-in-Class Anti-Tumor Agents
All present enzymatic activity of Identification of Novel, Potent and Selective GCN2 Inhibitors As First-in-Class Anti-Tumor Agents:
2.7.11.1; Protein crystallography data
The structure of Identification of Novel, Potent and Selective GCN2 Inhibitors As First-in-Class Anti-Tumor Agents, PDB code: 6n3o
was solved by
I.D.Hoffman,
J.Fujimoto,
O.Kurasawa,
T.Takagi,
M.G.Klein,
G.Kefala,
S.C.Ding,
D.R.Cary,
R.Mizojiri,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6n3o:
The structure of Identification of Novel, Potent and Selective GCN2 Inhibitors As First-in-Class Anti-Tumor Agents also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Identification of Novel, Potent and Selective GCN2 Inhibitors As First-in-Class Anti-Tumor Agents
(pdb code 6n3o). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Identification of Novel, Potent and Selective GCN2 Inhibitors As First-in-Class Anti-Tumor Agents, PDB code: 6n3o: Chlorine binding site 1 out of 1 in 6n3oGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Identification of Novel, Potent and Selective GCN2 Inhibitors As First-in-Class Anti-Tumor Agents
![]() Mono view ![]() Stereo pair view
Reference:
J.Fujimoto,
O.Kurasawa,
T.Takagi,
X.Liu,
H.Banno,
T.Kojima,
Y.Asano,
A.Nakamura,
T.Nambu,
A.Hata,
T.Ishii,
T.Sameshima,
Y.Debori,
M.Miyamoto,
M.G.Klein,
R.Tjhen,
B.C.Sang,
I.Levin,
S.W.Lane,
G.P.Snell,
K.Li,
G.Kefala,
I.D.Hoffman,
S.C.Ding,
D.R.Cary,
R.Mizojiri.
Identification of Novel, Potent, and Orally Available GCN2 Inhibitors with Type I Half Binding Mode. Acs Med.Chem.Lett. V. 10 1498 2019.
Page generated: Sun Jul 28 03:30:29 2024
ISSN: ISSN 1948-5875 PubMed: 31620240 DOI: 10.1021/ACSMEDCHEMLETT.9B00400 |
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