Atomistry » Chlorine » PDB 6nku-6nvh » 6nky
Atomistry »
  Chlorine »
    PDB 6nku-6nvh »
      6nky »

Chlorine in PDB 6nky: Ternary Complex Crystal Structure of K289M Variant of Dna Polymerase Beta with "Hot-Spot Sequence" with Beta-Gamma Chf Analogue of Dgtp

Enzymatic activity of Ternary Complex Crystal Structure of K289M Variant of Dna Polymerase Beta with "Hot-Spot Sequence" with Beta-Gamma Chf Analogue of Dgtp

All present enzymatic activity of Ternary Complex Crystal Structure of K289M Variant of Dna Polymerase Beta with "Hot-Spot Sequence" with Beta-Gamma Chf Analogue of Dgtp:
2.7.7.7;

Protein crystallography data

The structure of Ternary Complex Crystal Structure of K289M Variant of Dna Polymerase Beta with "Hot-Spot Sequence" with Beta-Gamma Chf Analogue of Dgtp, PDB code: 6nky was solved by V.K.Batra, S.H.Wilson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 21.98 / 2.09
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 50.643, 80.158, 55.251, 90.00, 107.89, 90.00
R / Rfree (%) 19.9 / 25.6

Other elements in 6nky:

The structure of Ternary Complex Crystal Structure of K289M Variant of Dna Polymerase Beta with "Hot-Spot Sequence" with Beta-Gamma Chf Analogue of Dgtp also contains other interesting chemical elements:

Fluorine (F) 1 atom
Magnesium (Mg) 1 atom
Sodium (Na) 3 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Ternary Complex Crystal Structure of K289M Variant of Dna Polymerase Beta with "Hot-Spot Sequence" with Beta-Gamma Chf Analogue of Dgtp (pdb code 6nky). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Ternary Complex Crystal Structure of K289M Variant of Dna Polymerase Beta with "Hot-Spot Sequence" with Beta-Gamma Chf Analogue of Dgtp, PDB code: 6nky:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in 6nky

Go back to Chlorine Binding Sites List in 6nky
Chlorine binding site 1 out of 3 in the Ternary Complex Crystal Structure of K289M Variant of Dna Polymerase Beta with "Hot-Spot Sequence" with Beta-Gamma Chf Analogue of Dgtp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Ternary Complex Crystal Structure of K289M Variant of Dna Polymerase Beta with "Hot-Spot Sequence" with Beta-Gamma Chf Analogue of Dgtp within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl405

b:46.0
occ:1.00
 CB A:ALA32 3.4 34.7 1.0
N A:HIS34 3.4 36.5 1.0
C A:ALA32 3.5 34.1 1.0
CA A:ALA32 3.5 34.8 1.0
CB A:HIS34 3.5 35.0 1.0
N A:LYS35 3.6 32.2 1.0
O A:ALA32 3.8 33.3 1.0
N A:ILE33 3.8 34.4 1.0
CA A:HIS34 3.9 38.5 1.0
CD2 A:HIS34 4.0 42.5 1.0
CG A:LYS35 4.1 34.3 1.0
CG A:HIS34 4.1 37.5 1.0
C A:HIS34 4.2 35.8 1.0
C A:ILE33 4.4 35.3 1.0
O A:HOH574 4.5 38.1 1.0
CB A:LYS35 4.6 33.0 1.0
O4 D:DT1 4.6 37.9 1.0
CA A:LYS35 4.7 31.0 1.0
C7 D:DT1 4.7 29.9 1.0
CA A:ILE33 4.8 39.6 1.0
CD A:LYS35 4.9 32.5 1.0
C4 D:DT1 5.0 34.8 1.0
N A:ALA32 5.0 33.6 1.0

Chlorine binding site 2 out of 3 in 6nky

Go back to Chlorine Binding Sites List in 6nky
Chlorine binding site 2 out of 3 in the Ternary Complex Crystal Structure of K289M Variant of Dna Polymerase Beta with "Hot-Spot Sequence" with Beta-Gamma Chf Analogue of Dgtp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Ternary Complex Crystal Structure of K289M Variant of Dna Polymerase Beta with "Hot-Spot Sequence" with Beta-Gamma Chf Analogue of Dgtp within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl406

b:54.3
occ:1.00
 N A:LEU82 3.1 34.7 1.0
NH1 A:ARG89 3.6 49.5 1.0
CA A:LYS81 3.7 44.1 1.0
C A:LYS81 3.8 42.4 1.0
NH2 A:ARG89 3.8 52.9 1.0
CD1 A:LEU85 4.0 35.6 1.0
CB A:LEU82 4.0 38.7 1.0
CA A:LEU82 4.0 42.1 1.0
O A:LEU82 4.0 39.6 1.0
CB A:LEU85 4.2 40.0 1.0
CB A:LYS81 4.2 47.0 1.0
CZ A:ARG89 4.2 53.0 1.0
C A:LEU82 4.5 43.1 1.0
CG A:LEU85 4.7 39.0 1.0
CG A:GLU86 4.7 52.6 1.0
O A:GLY80 4.8 43.2 1.0
CE1 A:PHE76 4.8 36.7 1.0
O A:LYS81 4.9 39.6 1.0
CD1 A:PHE76 4.9 38.0 1.0
N A:LYS81 4.9 40.4 1.0

Chlorine binding site 3 out of 3 in 6nky

Go back to Chlorine Binding Sites List in 6nky
Chlorine binding site 3 out of 3 in the Ternary Complex Crystal Structure of K289M Variant of Dna Polymerase Beta with "Hot-Spot Sequence" with Beta-Gamma Chf Analogue of Dgtp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Ternary Complex Crystal Structure of K289M Variant of Dna Polymerase Beta with "Hot-Spot Sequence" with Beta-Gamma Chf Analogue of Dgtp within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl407

b:47.2
occ:1.00
 NH2 A:ARG299 2.9 43.7 1.0
OG1 A:THR297 3.3 39.4 1.0
ND2 A:ASN294 3.4 30.5 1.0
NE A:ARG299 3.5 45.5 1.0
CZ A:ARG299 3.6 52.0 1.0
CG2 A:THR297 3.7 31.4 1.0
CB A:TYR296 4.0 32.0 1.0
OD1 A:ASN294 4.1 36.6 1.0
CB A:THR297 4.1 39.7 1.0
CG A:ASN294 4.2 33.6 1.0
CD2 A:TYR296 4.3 30.8 1.0
CG A:TYR296 4.5 32.4 1.0
O A:HOH555 4.7 37.4 1.0
N A:THR297 4.7 31.3 1.0
CD A:ARG299 4.8 37.9 1.0
NH1 A:ARG299 4.8 57.4 1.0

Reference:

V.K.Batra, S.H.Wilson. Ternary Complex Crystal Structure of K289M Variant of Dna Polymerase Beta with "Hot-Spot Sequence" with Beta-Gamma Chf Analogue of Dgtp To Be Published.
Page generated: Sat Jul 12 17:21:45 2025

Last articles

Mg in 3T5G
Mg in 3T3P
Mg in 3T4Y
Mg in 3T4R
Mg in 3T2Q
Mg in 3T2P
Mg in 3T3F
Mg in 3T34
Mg in 3T2S
Mg in 3T2D
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy