Chlorine in PDB 6o9g: Open State GLUA2 in Complex with Stz and Blocked By Agtx-636, After Micelle Signal Subtraction

The binding sites of Chlorine atom in the Open State GLUA2 in Complex with Stz and Blocked By Agtx-636, After Micelle Signal Subtraction (pdb code 6o9g). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Open State GLUA2 in Complex with Stz and Blocked By Agtx-636, After Micelle Signal Subtraction, PDB code: 6o9g:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Open State GLUA2 in Complex with Stz and Blocked By Agtx-636, After Micelle Signal Subtraction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Open State GLUA2 in Complex with Stz and Blocked By Agtx-636, After Micelle Signal Subtraction within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1302 b:0.4 occ:1.00 CL A:CYZ1302 0.0 0.4 1.0 C13 A:CYZ1302 1.8 0.4 1.0 C14 A:CYZ1302 2.7 0.4 1.0 C12 A:CYZ1302 2.8 0.4 1.0 O4 A:CYZ1302 3.1 0.4 1.0 OD1 A:ASP760 3.2 0.0 1.0 S2 A:CYZ1302 3.4 0.4 1.0 N3 A:CYZ1302 3.8 0.4 1.0 OG D:SER729 3.8 0.2 1.0 C11 A:CYZ1302 4.0 0.4 1.0 C10 A:CYZ1302 4.1 0.4 1.0 CB D:SER729 4.2 0.2 1.0 O A:PHE495 4.2 0.5 1.0 CG A:ASP760 4.3 0.0 1.0 C9 A:CYZ1302 4.5 0.4 1.0 CB A:LEU759 4.7 0.2 1.0 O3 A:CYZ1302 4.8 0.4 1.0 OD2 A:ASP760 4.9 0.0 1.0 NZ A:LYS763 4.9 0.4 1.0 CD A:LYS763 4.9 0.4 1.0

Chlorine binding site 2 out of 4 in the Open State GLUA2 in Complex with Stz and Blocked By Agtx-636, After Micelle Signal Subtraction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Open State GLUA2 in Complex with Stz and Blocked By Agtx-636, After Micelle Signal Subtraction within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1302 b:0.1 occ:1.00 CL B:CYZ1302 0.0 0.1 1.0 C13 B:CYZ1302 1.8 0.1 1.0 C14 B:CYZ1302 2.7 0.1 1.0 C12 B:CYZ1302 2.8 0.1 1.0 OD1 B:ASP760 3.1 0.2 1.0 O4 B:CYZ1302 3.2 0.1 1.0 S2 B:CYZ1302 3.2 0.1 1.0 N3 B:CYZ1302 3.4 0.1 1.0 CB B:LEU759 3.9 0.6 1.0 C11 B:CYZ1302 4.0 0.1 1.0 C10 B:CYZ1302 4.0 0.1 1.0 CG B:ASP760 4.1 0.2 1.0 OG C:SER729 4.1 1.0 1.0 N B:ASP760 4.2 0.2 1.0 C B:LEU759 4.4 0.6 1.0 C9 B:CYZ1302 4.5 0.1 1.0 CB C:SER729 4.6 1.0 1.0 CD1 B:LEU759 4.6 0.6 1.0 CA B:ASP760 4.6 0.2 1.0 OD2 B:ASP760 4.6 0.2 1.0 O3 B:CYZ1302 4.7 0.1 1.0 O B:PHE495 4.7 0.6 1.0 O B:LEU759 4.8 0.6 1.0 CA B:LEU759 4.8 0.6 1.0 CG B:LEU759 4.9 0.6 1.0 CB B:ASP760 5.0 0.2 1.0

Chlorine binding site 3 out of 4 in the Open State GLUA2 in Complex with Stz and Blocked By Agtx-636, After Micelle Signal Subtraction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Open State GLUA2 in Complex with Stz and Blocked By Agtx-636, After Micelle Signal Subtraction within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1302 b:1.0 occ:1.00 CL C:CYZ1302 0.0 1.0 1.0 C13 C:CYZ1302 1.8 1.0 1.0 C14 C:CYZ1302 2.7 1.0 1.0 C12 C:CYZ1302 2.8 1.0 1.0 O4 C:CYZ1302 3.1 1.0 1.0 OD1 C:ASP760 3.2 0.3 1.0 S2 C:CYZ1302 3.4 1.0 1.0 N3 C:CYZ1302 3.8 1.0 1.0 OG B:SER729 3.8 0.6 1.0 C11 C:CYZ1302 4.0 1.0 1.0 C10 C:CYZ1302 4.1 1.0 1.0 CB B:SER729 4.1 0.6 1.0 O C:PHE495 4.2 0.2 1.0 CG C:ASP760 4.3 0.3 1.0 C9 C:CYZ1302 4.5 1.0 1.0 CB C:LEU759 4.7 0.8 1.0 O3 C:CYZ1302 4.8 1.0 1.0 OD2 C:ASP760 4.9 0.3 1.0 NZ C:LYS763 4.9 1.0 1.0 CD C:LYS763 4.9 1.0 1.0

Chlorine binding site 4 out of 4 in the Open State GLUA2 in Complex with Stz and Blocked By Agtx-636, After Micelle Signal Subtraction


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Open State GLUA2 in Complex with Stz and Blocked By Agtx-636, After Micelle Signal Subtraction within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl1302 b:0.3 occ:1.00 CL D:CYZ1302 0.0 0.3 1.0 C13 D:CYZ1302 1.8 0.3 1.0 C14 D:CYZ1302 2.7 0.3 1.0 C12 D:CYZ1302 2.8 0.3 1.0 OD1 D:ASP760 3.1 0.1 1.0 S2 D:CYZ1302 3.2 0.3 1.0 O4 D:CYZ1302 3.2 0.3 1.0 N3 D:CYZ1302 3.4 0.3 1.0 CB D:LEU759 3.9 0.2 1.0 C11 D:CYZ1302 4.0 0.3 1.0 C10 D:CYZ1302 4.0 0.3 1.0 CG D:ASP760 4.1 0.1 1.0 OG A:SER729 4.1 0.2 1.0 N D:ASP760 4.3 0.1 1.0 C D:LEU759 4.4 0.2 1.0 C9 D:CYZ1302 4.5 0.3 1.0 CB A:SER729 4.5 0.2 1.0 CD1 D:LEU759 4.6 0.2 1.0 CA D:ASP760 4.6 0.1 1.0 OD2 D:ASP760 4.6 0.1 1.0 O3 D:CYZ1302 4.7 0.3 1.0 O D:PHE495 4.7 0.6 1.0 O D:LEU759 4.8 0.2 1.0 CA D:LEU759 4.8 0.2 1.0 CG D:LEU759 4.9 0.2 1.0 CB D:ASP760 5.0 0.1 1.0

E.C.Twomey, M.V.Yelshanskaya, A.A.Vassilevski, A.I.Sobolevsky. Mechanisms of Channel Block in Calcium-Permeable Ampa Receptors. Neuron V. 99 956 2018.
ISSN: ISSN 1097-4199
PubMed: 30122377
DOI: 10.1016/J.NEURON.2018.07.027