Atomistry » Chlorine » PDB 6o9g-6ok0 » 6od5
Atomistry »
  Chlorine »
    PDB 6o9g-6ok0 »
      6od5 »

Chlorine in PDB 6od5: Human TCF4 C-Terminal Bhlh Domain in Complex with 12-Bp Oligonucleotide Containing E-Box Sequence with 5-Carboxylcytosines

Protein crystallography data

The structure of Human TCF4 C-Terminal Bhlh Domain in Complex with 12-Bp Oligonucleotide Containing E-Box Sequence with 5-Carboxylcytosines, PDB code: 6od5 was solved by J.R.Horton, X.Cheng, J.Yang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 36.66 / 2.05
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 44.677, 44.757, 54.640, 78.63, 78.88, 79.27
R / Rfree (%) 23.4 / 28

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Human TCF4 C-Terminal Bhlh Domain in Complex with 12-Bp Oligonucleotide Containing E-Box Sequence with 5-Carboxylcytosines (pdb code 6od5). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human TCF4 C-Terminal Bhlh Domain in Complex with 12-Bp Oligonucleotide Containing E-Box Sequence with 5-Carboxylcytosines, PDB code: 6od5:

Chlorine binding site 1 out of 1 in 6od5

Go back to Chlorine Binding Sites List in 6od5
Chlorine binding site 1 out of 1 in the Human TCF4 C-Terminal Bhlh Domain in Complex with 12-Bp Oligonucleotide Containing E-Box Sequence with 5-Carboxylcytosines


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human TCF4 C-Terminal Bhlh Domain in Complex with 12-Bp Oligonucleotide Containing E-Box Sequence with 5-Carboxylcytosines within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl702

b:56.6
occ:1.00
O A:HOH815 3.3 33.4 1.0
NH1 A:ARG570 3.5 37.6 1.0
CD A:ARG570 3.5 33.5 1.0
N A:HIS567 3.7 43.7 1.0
CA A:HIS567 3.8 42.7 1.0
CB A:HIS567 4.4 46.4 1.0
NE A:ARG570 4.5 34.0 1.0
CZ A:ARG570 4.5 36.2 1.0
CG A:ARG570 4.6 30.6 1.0
C A:HIS567 5.0 40.6 1.0
O A:HOH812 5.0 32.0 1.0

Reference:

J.Yang, J.R.Horton, J.Li, Y.Huang, X.Zhang, R.M.Blumenthal, X.Cheng. Structural Basis For Preferential Binding of Human TCF4 to Dna Containing 5-Carboxylcytosine. Nucleic Acids Res. V. 47 8375 2019.
ISSN: ESSN 1362-4962
PubMed: 31081034
DOI: 10.1093/NAR/GKZ381
Page generated: Sat Jul 12 17:49:04 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy