Chlorine in PDB 6ogn: Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with SGC8158 Chemical Probe

Enzymatic activity of Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with SGC8158 Chemical Probe

All present enzymatic activity of Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with SGC8158 Chemical Probe:
2.1.1.321;

Protein crystallography data

The structure of Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with SGC8158 Chemical Probe, PDB code: 6ogn was solved by L.Halabelian, A.Dong, H.Zeng, Y.Li, A.Hutchinson, A.Seitova, C.Bountra, A.M.Edwards, C.H.Arrowsmith, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	47.03 / 2.40
*Space group*	P 4₃ 2₁ 2
*Cell size a, b, c (Å), α, β, γ (°)*	97.813, 97.813, 169.539, 90.00, 90.00, 90.00
*R / R_free (%)*	20.8 / 26.1

Other elements in 6ogn:

The structure of Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with SGC8158 Chemical Probe also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with SGC8158 Chemical Probe (pdb code 6ogn). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with SGC8158 Chemical Probe, PDB code: 6ogn:

Chlorine binding site 1 out of 1 in 6ogn

Go back to

Chlorine Binding Sites List in 6ogn

Chlorine binding site 1 out of 1 in the Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with SGC8158 Chemical Probe

Mono view

Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with SGC8158 Chemical Probe within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Cl702 b:92.8 occ:1.00	CL	A:MJ7702	0.0	92.8	1.0
	C23	A:MJ7702	1.8	79.5	1.0
	C24	A:MJ7702	2.7	70.7	1.0
	C22	A:MJ7702	2.7	65.1	1.0
	CE	A:MET286	3.2	63.9	1.0
	CG1	A:ILE284	3.5	62.5	1.0
	SG	A:CYS294	3.6	79.6	1.0
	CE2	A:TYR48	3.7	54.9	1.0
	C25	A:MJ7702	4.0	75.5	1.0
	C21	A:MJ7702	4.0	65.1	1.0
	CG	A:ARG44	4.1	73.7	1.0
	CB	A:CYS294	4.3	59.7	1.0
	CD2	A:TYR48	4.3	49.4	1.0
	CZ	A:TYR48	4.4	45.8	1.0
	CB	A:ILE284	4.4	57.8	1.0
	OH	A:TYR48	4.5	51.1	1.0
	C20	A:MJ7702	4.5	69.7	1.0
	SD	A:MET286	4.7	61.2	1.0
	CB	A:ARG44	4.8	60.9	1.0
	CG2	A:ILE284	4.8	60.5	1.0
	CA	A:ARG44	4.8	56.8	1.0
	CD	A:ARG44	5.0	85.0	1.0

Reference:

L.Halabelian, A.Dong, H.Zeng, Y.Li, A.Hutchinson, A.Seitova, C.Bountra, A.M.Edwards, C.H.Arrowsmith. Crystal Structure of Mouse Protein Arginine Methyltransferase 7 in Complex with SGC8158 Chemical Probe To Be Published.

Page generated: Mon Jul 29 12:40:45 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy