Chlorine in PDB 6pg6: WDR5DELTA23 Bound to N-(4-(5-(Hydroxymethyl)-1H-Imidazol-2-Yl)Butyl) Acetamide

The structure of WDR5DELTA23 Bound to N-(4-(5-(Hydroxymethyl)-1H-Imidazol-2-Yl)Butyl) Acetamide, PDB code: 6pg6 was solved by M.L.Dennis, T.S.Peat, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.74 / 1.68
Space group	I 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	112.366, 46.974, 129.274, 90.00, 112.75, 90.00
R / Rfree (%)	16.5 / 19.3

The binding sites of Chlorine atom in the WDR5DELTA23 Bound to N-(4-(5-(Hydroxymethyl)-1H-Imidazol-2-Yl)Butyl) Acetamide (pdb code 6pg6). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the WDR5DELTA23 Bound to N-(4-(5-(Hydroxymethyl)-1H-Imidazol-2-Yl)Butyl) Acetamide, PDB code: 6pg6:

Chlorine binding site 1 out of 1 in the WDR5DELTA23 Bound to N-(4-(5-(Hydroxymethyl)-1H-Imidazol-2-Yl)Butyl) Acetamide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of WDR5DELTA23 Bound to N-(4-(5-(Hydroxymethyl)-1H-Imidazol-2-Yl)Butyl) Acetamide within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:29.8 occ:1.00 O A:HOH707 2.6 32.3 1.0 O A:HOH755 2.7 23.6 1.0 ND2 A:ASN265 3.2 16.8 1.0 N A:CYS309 3.3 11.4 1.0 O A:HOH505 3.6 27.9 1.0 O A:HOH656 3.7 13.8 1.0 O A:CYS309 3.8 12.5 1.0 CA A:ALA308 3.9 10.5 1.0 CG A:ASN265 4.0 16.4 1.0 O A:HOH621 4.0 13.7 1.0 NZ A:LYS221 4.0 17.0 1.0 C A:ALA308 4.1 10.8 1.0 CB A:ASN265 4.1 14.7 1.0 CA A:CYS309 4.2 12.3 1.0 CB A:CYS309 4.2 12.7 1.0 O A:HOH681 4.3 19.4 1.0 CB A:ALA308 4.4 11.1 1.0 O A:HOH734 4.4 31.2 1.0 C A:CYS309 4.5 12.2 1.0 O A:HOH644 4.8 13.9 1.0 SG A:CYS309 4.8 14.1 1.0 O A:HOH742 4.9 35.2 1.0 OD1 A:ASN265 5.0 21.1 1.0

M.L.Dennis, B.J.Morrow, O.Dolezal, A.N.Cuzzupe, A.E.Stupple, J.Newman, J.Bentley, M.Hattarki, S.D.Nuttall, R.C.Foitzik, I.P.Street, P.A.Stupple, B.J.Monahan, T.S.Peat. Fragment Screening For A Protein-Protein Interaction Inhibitor to WDR5. Struct Dyn. V. 6 64701 2019.
ISSN: ESSN 2329-7778
PubMed: 31768400
DOI: 10.1063/1.5122849