Chlorine in PDB 6q8f: Nterminal Domain of Human SMU1

The structure of Nterminal Domain of Human SMU1, PDB code: 6q8f was solved by L.Tengo, L.Le Corre, G.Fournier, U.Ashraf, P.Busca, M.-A.Rameix-Welti, C.Gravier-Pelletier, R.W.H.Ruigrok, Y.Jacob, P.-O.Vidalain, N.Pietrancosta, N.Naffakh, A.A.Mccarthy, T.Crepin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.14 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	40.183, 41.225, 123.599, 90.00, 91.48, 90.00
R / Rfree (%)	17.4 / 21.4

The binding sites of Chlorine atom in the Nterminal Domain of Human SMU1 (pdb code 6q8f). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Nterminal Domain of Human SMU1, PDB code: 6q8f:

Chlorine binding site 1 out of 1 in the Nterminal Domain of Human SMU1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Nterminal Domain of Human SMU1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl601 b:46.1 occ:1.00 NE1 B:TRP171 2.9 25.9 1.0 O B:HOH709 3.4 42.5 1.0 CD1 B:TRP171 3.4 20.3 1.0 CE2 B:TRP171 4.1 22.9 1.0 NE2 B:GLN175 4.4 26.2 1.0 CZ2 B:TRP171 4.7 28.3 1.0 CG B:TRP171 4.8 17.9 1.0

U.Ashraf, L.Tengo, L.Le Corre, G.Fournier, P.Busca, A.A.Mccarthy, M.A.Rameix-Welti, C.Gravier-Pelletier, R.W.H.Ruigrok, Y.Jacob, P.O.Vidalain, N.Pietrancosta, T.Crepin, N.Naffakh. Destabilization of the Human Red-SMU1 Splicing Complex As A Basis For Host-Directed Antiinfluenza Strategy. Proc.Natl.Acad.Sci.Usa V. 116 10968 2019.
ISSN: ESSN 1091-6490
PubMed: 31076555
DOI: 10.1073/PNAS.1901214116