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Atomistry » Chlorine » PDB 6s06-6sa4 » 6s7h | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 6s06-6sa4 » 6s7h » |
Chlorine in PDB 6s7h: Human CD73 (5'-Nucleotidase) in Complex with PSB12489 (An Aopcp Derivative) in the Closed StateEnzymatic activity of Human CD73 (5'-Nucleotidase) in Complex with PSB12489 (An Aopcp Derivative) in the Closed State
All present enzymatic activity of Human CD73 (5'-Nucleotidase) in Complex with PSB12489 (An Aopcp Derivative) in the Closed State:
3.1.3.5; Protein crystallography data
The structure of Human CD73 (5'-Nucleotidase) in Complex with PSB12489 (An Aopcp Derivative) in the Closed State, PDB code: 6s7h
was solved by
J.Pippel,
N.Strater,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6s7h:
The structure of Human CD73 (5'-Nucleotidase) in Complex with PSB12489 (An Aopcp Derivative) in the Closed State also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human CD73 (5'-Nucleotidase) in Complex with PSB12489 (An Aopcp Derivative) in the Closed State
(pdb code 6s7h). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human CD73 (5'-Nucleotidase) in Complex with PSB12489 (An Aopcp Derivative) in the Closed State, PDB code: 6s7h: Chlorine binding site 1 out of 1 in 6s7hGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Human CD73 (5'-Nucleotidase) in Complex with PSB12489 (An Aopcp Derivative) in the Closed State
![]() Mono view ![]() Stereo pair view
Reference:
S.Bhattarai,
J.Pippel,
A.Meyer,
M.Freundlieb,
C.Schmies,
A.Abdelrahman,
A.Fiene,
S.Y.Lee,
H.Zimmermann,
A.El-Tayeb,
G.G.Yegutkin,
N.Strater,
C.E.Muller.
X-Ray Co-Crystal Structure Guides the Way to Subnanomolar Competitive Ecto-5'-Nucleotidase (CD73) Inhibitors For Cancer Immunotherapy Adv Ther 2019.
Page generated: Mon Jul 29 14:50:24 2024
DOI: 10.1002/ADTP.201900075 |
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