Chlorine in PDB 6tqa: X-Ray Structure of Roquin Roq Domain in Complex with A UCP3 CDE2 Sl Rna Motif

All present enzymatic activity of X-Ray Structure of Roquin Roq Domain in Complex with A UCP3 CDE2 Sl Rna Motif:
2.3.2.27;

The structure of X-Ray Structure of Roquin Roq Domain in Complex with A UCP3 CDE2 Sl Rna Motif, PDB code: 6tqa was solved by O.Binas, J.-N.Tants, S.A.Peter, R.Janowski, E.Davydova, J.Braun, D.Niessing, H.Schwalbe, J.E.Weigand, A.Schlundt, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.40 / 2.40
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	44.530, 160.660, 68.010, 90.00, 107.96, 90.00
R / Rfree (%)	19.7 / 25.9

The structure of X-Ray Structure of Roquin Roq Domain in Complex with A UCP3 CDE2 Sl Rna Motif also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Chlorine atom in the X-Ray Structure of Roquin Roq Domain in Complex with A UCP3 CDE2 Sl Rna Motif (pdb code 6tqa). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the X-Ray Structure of Roquin Roq Domain in Complex with A UCP3 CDE2 Sl Rna Motif, PDB code: 6tqa:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the X-Ray Structure of Roquin Roq Domain in Complex with A UCP3 CDE2 Sl Rna Motif


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of X-Ray Structure of Roquin Roq Domain in Complex with A UCP3 CDE2 Sl Rna Motif within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:71.0 occ:1.00 O C:HOH422 3.6 36.3 1.0 OG1 A:THR258 4.9 48.4 1.0 CB A:ALA216 4.9 37.9 1.0

Chlorine binding site 2 out of 3 in the X-Ray Structure of Roquin Roq Domain in Complex with A UCP3 CDE2 Sl Rna Motif


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of X-Ray Structure of Roquin Roq Domain in Complex with A UCP3 CDE2 Sl Rna Motif within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:45.9 occ:1.00 CD A:LYS256 3.3 45.2 1.0 NH2 B:ARG233 3.3 44.0 1.0 N A:GLU271 3.4 40.6 1.0 CA A:LYS270 3.7 38.6 1.0 CE A:LYS256 3.7 47.5 1.0 CG A:GLU271 3.9 46.6 1.0 C A:LYS270 4.0 38.8 1.0 CD B:ARG233 4.0 40.9 1.0 CB A:LYS270 4.0 38.7 1.0 NZ A:LYS256 4.2 48.0 0.7 CG A:LYS256 4.3 43.9 1.0 CB A:GLU271 4.3 45.1 1.0 CG A:LYS270 4.4 38.6 1.0 CZ B:ARG233 4.4 42.6 1.0 CA A:GLU271 4.5 42.9 1.0 OE1 A:GLU272 4.5 44.5 1.0 CG B:ARG233 4.5 40.2 1.0 CD A:GLU271 4.6 48.5 0.8 CB A:LYS256 4.6 42.4 1.0 NE B:ARG233 4.7 41.1 1.0 OE1 A:GLU271 4.9 50.6 0.8 N A:LYS270 4.9 38.1 1.0 O A:LEU269 4.9 38.3 1.0

Chlorine binding site 3 out of 3 in the X-Ray Structure of Roquin Roq Domain in Complex with A UCP3 CDE2 Sl Rna Motif


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of X-Ray Structure of Roquin Roq Domain in Complex with A UCP3 CDE2 Sl Rna Motif within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl101 b:49.7 occ:1.00 O F:HOH217 2.5 50.7 1.0 O B:HOH417 2.5 38.7 1.0 O F:HOH208 2.7 38.8 1.0 N7 F:A8 2.7 49.8 1.0 O B:HOH428 3.0 58.9 1.0 C8 F:A8 3.5 51.2 1.0 C5 F:A8 3.7 51.7 1.0 N6 F:A8 3.9 52.0 1.0 OP2 F:A8 4.0 56.2 1.0 OG1 B:THR240 4.0 41.0 1.0 O F:HOH222 4.2 40.0 1.0 C6 F:A8 4.2 51.6 1.0 CA B:THR240 4.3 38.7 1.0 O B:HOH438 4.5 36.2 1.0 O B:LYS239 4.5 38.3 1.0 N B:THR240 4.6 39.7 1.0 N9 F:A8 4.6 53.3 1.0 C B:LYS239 4.7 39.8 1.0 C5 F:U7 4.7 52.1 1.0 CB B:THR240 4.7 39.9 1.0 C4 F:A8 4.7 53.4 1.0 N7 F:A9 4.9 52.7 1.0 C4 F:U7 4.9 51.9 1.0 C6 F:U7 5.0 52.9 1.0

R.Janowski, E.Davydova, A.Schlundt, D.Niessing. Structural Basis For the Recognition of (Linear and) Non-Linear Au-Rich Elements By Roquin Nucleic Acids Res. 2020.
ISSN: ESSN 1362-4962