Atomistry » Chlorine » PDB 6u69-6udv » 6ub9
Atomistry »
  Chlorine »
    PDB 6u69-6udv »
      6ub9 »

Chlorine in PDB 6ub9: Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form

Enzymatic activity of Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form

All present enzymatic activity of Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form:
4.2.1.20;

Protein crystallography data

The structure of Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form, PDB code: 6ub9 was solved by C.Chang, K.Michalska, N.I.Maltseva, R.Jedrzejczak, P.Mccarren, P.P.Nag, A.Joachimiak, K.Satchell, Center For Structural Genomics Of Infectiousdiseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.89 / 2.78
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 135.373, 159.619, 164.932, 90.00, 90.00, 90.00
R / Rfree (%) 16.9 / 21

Other elements in 6ub9:

The structure of Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form also contains other interesting chemical elements:

Fluorine (F) 12 atoms
Caesium (Cs) 4 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form (pdb code 6ub9). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form, PDB code: 6ub9:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 6ub9

Go back to Chlorine Binding Sites List in 6ub9
Chlorine binding site 1 out of 4 in the Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl502

b:40.5
occ:1.00
CL1 B:H9V502 0.0 40.5 1.0
C10 B:H9V502 1.7 38.1 1.0
C9 B:H9V502 2.7 37.9 1.0
C11 B:H9V502 2.7 37.2 1.0
CE2 B:PHE211 3.3 24.1 1.0
CD2 B:PHE211 3.4 25.1 1.0
CB B:PHE202 3.5 31.5 1.0
CZ B:PHE211 3.5 23.5 1.0
CG B:PHE211 3.6 21.5 1.0
CG B:PHE202 3.6 31.6 1.0
CE1 B:PHE211 3.7 24.5 1.0
CD1 B:PHE211 3.7 21.3 1.0
CD2 B:TYR200 3.8 34.0 1.0
CE2 B:TYR200 3.9 34.7 1.0
C8 B:H9V502 4.0 37.9 1.0
C12 B:H9V502 4.0 38.2 1.0
CD2 B:PHE202 4.0 31.4 1.0
CD1 B:PHE202 4.1 32.0 1.0
CD B:PRO208 4.2 26.4 1.0
CG B:TYR200 4.3 33.6 1.0
CZ B:TYR200 4.4 35.0 1.0
CB B:PHE211 4.4 23.6 1.0
C7 B:H9V502 4.5 39.5 1.0
CZ3 B:TRP191 4.6 27.7 1.0
CA B:PHE202 4.7 32.1 1.0
CG B:PRO208 4.8 26.9 1.0
CE2 B:PHE202 4.8 31.3 1.0
CD1 B:TYR200 4.8 34.3 1.0
CE1 B:TYR200 4.9 33.7 1.0
CE1 B:PHE202 4.9 31.9 1.0
F2 B:H9V502 4.9 39.1 1.0
O B:TYR200 5.0 34.6 1.0
N B:PHE202 5.0 30.4 1.0
CB B:TYR200 5.0 33.3 1.0
F1 B:H9V502 5.0 38.1 1.0

Chlorine binding site 2 out of 4 in 6ub9

Go back to Chlorine Binding Sites List in 6ub9
Chlorine binding site 2 out of 4 in the Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl502

b:59.1
occ:0.76
CL1 D:H9V502 0.0 59.1 0.8
C10 D:H9V502 1.7 60.6 0.8
C11 D:H9V502 2.7 60.7 0.8
C9 D:H9V502 2.7 60.7 0.8
CE2 D:PHE211 3.3 28.5 1.0
CD2 D:PHE211 3.3 27.6 1.0
CG D:PHE202 3.5 42.8 1.0
CZ D:PHE211 3.5 27.6 1.0
CB D:PHE202 3.6 38.2 1.0
CG D:PHE211 3.7 26.8 1.0
CD1 D:PHE202 3.7 44.5 1.0
CD2 D:TYR200 3.7 30.2 1.0
CE1 D:PHE211 3.9 27.8 1.0
CE2 D:TYR200 3.9 28.5 1.0
CD1 D:PHE211 3.9 27.4 1.0
C12 D:H9V502 4.0 60.3 0.8
CD2 D:PHE202 4.0 43.4 1.0
C8 D:H9V502 4.0 60.0 0.8
CD D:PRO208 4.2 29.7 1.0
CG D:TYR200 4.3 28.8 1.0
CE1 D:PHE202 4.3 45.0 1.0
CZ3 D:TRP191 4.4 24.4 1.0
CB D:PHE211 4.5 27.5 1.0
CZ D:TYR200 4.6 33.4 1.0
C7 D:H9V502 4.6 59.8 0.8
CE2 D:PHE202 4.6 44.4 1.0
CA D:PHE202 4.7 33.0 1.0
CZ D:PHE202 4.8 45.2 1.0
CG D:PRO208 4.8 27.8 1.0
CB D:TYR200 4.8 28.9 1.0
CD1 D:TYR200 4.9 29.6 1.0
F1 D:H9V502 4.9 60.8 0.8
CE3 D:TRP191 5.0 24.6 1.0

Chlorine binding site 3 out of 4 in 6ub9

Go back to Chlorine Binding Sites List in 6ub9
Chlorine binding site 3 out of 4 in the Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Cl502

b:43.1
occ:1.00
CL1 F:H9V502 0.0 43.1 1.0
C10 F:H9V502 1.7 43.8 1.0
C9 F:H9V502 2.7 43.2 1.0
C11 F:H9V502 2.7 43.8 1.0
CD2 F:PHE211 3.4 25.9 1.0
CE2 F:PHE211 3.4 24.6 1.0
CB F:PHE202 3.4 33.8 1.0
CG F:PHE202 3.5 33.5 1.0
CG F:PHE211 3.6 26.8 1.0
CZ F:PHE211 3.7 26.9 1.0
CD1 F:PHE211 3.8 24.4 1.0
CD2 F:PHE202 3.8 32.9 1.0
CE1 F:PHE211 3.8 23.6 1.0
CD2 F:TYR200 3.9 34.5 1.0
C8 F:H9V502 4.0 44.6 1.0
C12 F:H9V502 4.0 44.5 1.0
CD F:PRO208 4.0 31.8 1.0
CE2 F:TYR200 4.1 35.1 1.0
CD1 F:PHE202 4.1 32.3 1.0
CB F:PHE211 4.4 22.9 1.0
CG F:TYR200 4.5 32.6 1.0
C7 F:H9V502 4.6 45.8 1.0
CE2 F:PHE202 4.6 32.7 1.0
CZ3 F:TRP191 4.6 29.1 1.0
CG F:PRO208 4.7 32.6 1.0
CZ F:TYR200 4.8 34.8 1.0
CA F:PHE202 4.8 33.8 1.0
CE1 F:PHE202 4.8 32.3 1.0
CB F:TYR200 5.0 31.6 1.0

Chlorine binding site 4 out of 4 in 6ub9

Go back to Chlorine Binding Sites List in 6ub9
Chlorine binding site 4 out of 4 in the Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Cl503

b:42.7
occ:1.00
CL1 H:H9V503 0.0 42.7 1.0
C10 H:H9V503 1.7 41.7 1.0
C11 H:H9V503 2.7 41.2 1.0
C9 H:H9V503 2.7 40.6 1.0
CD2 H:PHE211 3.4 23.9 1.0
CE2 H:PHE211 3.4 22.6 1.0
CB H:PHE202 3.4 28.1 1.0
CG H:PHE211 3.6 21.6 1.0
CG H:PHE202 3.6 27.1 1.0
CZ H:PHE211 3.6 22.4 1.0
CD1 H:PHE211 3.7 23.5 1.0
CE1 H:PHE211 3.7 23.6 1.0
C12 H:H9V503 4.0 42.3 1.0
C8 H:H9V503 4.0 40.1 1.0
CD1 H:PHE202 4.0 27.3 1.0
CD2 H:TYR200 4.0 29.8 1.0
CD2 H:PHE202 4.0 24.1 1.0
CE2 H:TYR200 4.2 30.8 1.0
CD H:PRO208 4.2 23.2 1.0
CB H:PHE211 4.4 21.3 1.0
CG H:TYR200 4.4 28.1 1.0
C7 H:H9V503 4.5 40.9 1.0
CZ3 H:TRP191 4.7 26.2 1.0
CZ H:TYR200 4.7 31.5 1.0
CA H:PHE202 4.7 29.2 1.0
CG H:PRO208 4.8 23.6 1.0
CE1 H:PHE202 4.8 27.6 1.0
CE2 H:PHE202 4.8 25.4 1.0
CD1 H:TYR200 4.9 29.0 1.0
F1 H:H9V503 5.0 45.6 1.0
O H:TYR200 5.0 26.7 1.0
CB H:TYR200 5.0 27.8 1.0
CA H:GLY207 5.0 26.9 1.0
F2 H:H9V503 5.0 40.5 1.0

Reference:

C.Chang, K.Michalska, N.I.Maltseva, R.Jedrzejczak, P.Mccarren, P.P.Nag, A.Joachimiak, K.Satchell, Center For Structural Genomics Of Infectious Diseases(Csgid). Crystal Structure of Tryptophan Synthase From M. Tuberculosis - Aminoacrylate- and BRD6309-Bound Form To Be Published.
Page generated: Sat Jul 12 20:28:29 2025

Last articles

Fe in 6CZ6
Fe in 6CYY
Fe in 6CYJ
Fe in 6CYP
Fe in 6CYS
Fe in 6CXV
Fe in 6CXU
Fe in 6CSB
Fe in 6CWW
Fe in 6CVC
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy