Chlorine in PDB 6vcw: Crystal Structure of Medicago Truncatula S-Adenosylmethionine Synthase 3A (MTMAT3A)

All present enzymatic activity of Crystal Structure of Medicago Truncatula S-Adenosylmethionine Synthase 3A (MTMAT3A):
2.5.1.6;

The structure of Crystal Structure of Medicago Truncatula S-Adenosylmethionine Synthase 3A (MTMAT3A), PDB code: 6vcw was solved by B.Sekula, M.Ruszkowski, Z.Dauter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.99 / 1.40
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	111.602, 62.042, 102.284, 90.00, 90.02, 90.00
R / Rfree (%)	11.5 / 15.9

The structure of Crystal Structure of Medicago Truncatula S-Adenosylmethionine Synthase 3A (MTMAT3A) also contains other interesting chemical elements:

Magnesium

(Mg)

4 atoms

The binding sites of Chlorine atom in the Crystal Structure of Medicago Truncatula S-Adenosylmethionine Synthase 3A (MTMAT3A) (pdb code 6vcw). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Medicago Truncatula S-Adenosylmethionine Synthase 3A (MTMAT3A), PDB code: 6vcw:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Medicago Truncatula S-Adenosylmethionine Synthase 3A (MTMAT3A)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Medicago Truncatula S-Adenosylmethionine Synthase 3A (MTMAT3A) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:25.6 occ:1.00 O A:HOH708 3.2 36.4 1.0 O A:HOH558 3.3 27.0 1.0 NH2 A:ARG70 3.4 14.8 1.0 N A:VAL92 3.5 12.8 1.0 CA A:LYS91 3.8 13.9 1.0 O A:CYS90 3.8 16.5 1.0 O A:VAL92 4.0 17.1 1.0 C A:LYS91 4.1 15.3 1.0 OE2 A:GLU66 4.5 22.6 1.0 CA A:VAL92 4.5 13.5 1.0 C A:CYS90 4.6 12.5 1.0 N A:LYS91 4.6 13.1 1.0 CB A:LYS91 4.7 17.7 1.0 C A:VAL92 4.7 14.2 1.0 CZ A:ARG70 4.7 12.6 1.0 CB A:VAL92 4.9 13.8 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Medicago Truncatula S-Adenosylmethionine Synthase 3A (MTMAT3A)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Medicago Truncatula S-Adenosylmethionine Synthase 3A (MTMAT3A) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl403 b:40.5 occ:1.00 O B:HOH893 3.2 49.1 1.0 N B:GLU66 3.4 16.6 1.0 N B:TYR65 3.5 16.2 1.0 OD1 B:ASN64 3.7 22.4 1.0 CB B:TYR65 4.0 18.1 1.0 CB B:GLU66 4.0 16.7 1.0 CG2 B:VAL94 4.1 23.2 1.0 CA B:TYR65 4.1 17.6 1.0 C B:ASN64 4.2 16.9 1.0 O B:HOH865 4.2 45.6 1.0 C B:TYR65 4.2 16.0 1.0 CA B:GLU66 4.3 15.6 1.0 CA B:ASN64 4.4 19.8 1.0 CG B:ASN64 4.4 19.6 1.0 CG1 B:VAL94 4.4 20.8 1.0 CD2 B:TYR65 4.5 22.3 1.0 CB B:VAL94 4.5 19.5 1.0 CG B:TYR65 4.7 18.1 1.0 O B:VAL63 5.0 30.4 1.0

B.Sekula, M.Ruszkowski, Z.Dauter. S-Adenosylmethionine Synthases in Plants: Structural Characterization of Type I and II Isoenzymes From Arabidopsis Thaliana and Medicago Truncatula. Int.J.Biol.Macromol. 2020.
ISSN: ISSN 0141-8130
PubMed: 32057875
DOI: 10.1016/J.IJBIOMAC.2020.02.100