Atomistry » Chlorine » PDB 6x6r-6xin » 6xcx
Atomistry »
  Chlorine »
    PDB 6x6r-6xin »
      6xcx »

Chlorine in PDB 6xcx: Nitric Oxide Synthase From Bacillus Subtilis in Complex with N2-((3- ((2-Aminoquinolin-7-Yl)Methoxy)Phenoxy)Methyl)Pyridine-2,6-Diamine

Enzymatic activity of Nitric Oxide Synthase From Bacillus Subtilis in Complex with N2-((3- ((2-Aminoquinolin-7-Yl)Methoxy)Phenoxy)Methyl)Pyridine-2,6-Diamine

All present enzymatic activity of Nitric Oxide Synthase From Bacillus Subtilis in Complex with N2-((3- ((2-Aminoquinolin-7-Yl)Methoxy)Phenoxy)Methyl)Pyridine-2,6-Diamine:
1.14.14.47;

Protein crystallography data

The structure of Nitric Oxide Synthase From Bacillus Subtilis in Complex with N2-((3- ((2-Aminoquinolin-7-Yl)Methoxy)Phenoxy)Methyl)Pyridine-2,6-Diamine, PDB code: 6xcx was solved by M.C.Lewis, T.L.Poulos, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 37.65 / 2.25
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 80.67, 94.98, 61.79, 90, 90, 90
R / Rfree (%) 17.9 / 22

Other elements in 6xcx:

The structure of Nitric Oxide Synthase From Bacillus Subtilis in Complex with N2-((3- ((2-Aminoquinolin-7-Yl)Methoxy)Phenoxy)Methyl)Pyridine-2,6-Diamine also contains other interesting chemical elements:

Iron (Fe) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Nitric Oxide Synthase From Bacillus Subtilis in Complex with N2-((3- ((2-Aminoquinolin-7-Yl)Methoxy)Phenoxy)Methyl)Pyridine-2,6-Diamine (pdb code 6xcx). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Nitric Oxide Synthase From Bacillus Subtilis in Complex with N2-((3- ((2-Aminoquinolin-7-Yl)Methoxy)Phenoxy)Methyl)Pyridine-2,6-Diamine, PDB code: 6xcx:

Chlorine binding site 1 out of 1 in 6xcx

Go back to Chlorine Binding Sites List in 6xcx
Chlorine binding site 1 out of 1 in the Nitric Oxide Synthase From Bacillus Subtilis in Complex with N2-((3- ((2-Aminoquinolin-7-Yl)Methoxy)Phenoxy)Methyl)Pyridine-2,6-Diamine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Nitric Oxide Synthase From Bacillus Subtilis in Complex with N2-((3- ((2-Aminoquinolin-7-Yl)Methoxy)Phenoxy)Methyl)Pyridine-2,6-Diamine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl902

b:39.5
occ:1.00
 OH A:TYR239 2.9 26.5 1.0
O A:HOH1097 3.0 42.8 1.0
ND2 A:ASN248 3.1 27.4 1.0
O A:HOH1020 3.1 33.8 1.0
NE2 A:GLN129 3.3 30.8 1.0
CE1 A:TYR239 3.5 24.8 1.0
CZ A:TYR239 3.6 25.1 1.0
OD1 A:ASN248 3.8 29.9 1.0
CG A:ASN248 3.8 28.9 1.0
OH A:TYR213 3.9 26.5 1.0
CD A:GLN129 4.2 32.1 1.0
OE1 A:GLN129 4.2 30.4 1.0
O A:HOH1006 4.3 33.1 1.0
O A:HOH1034 4.3 39.7 1.0
NE1 A:TRP212 4.7 25.8 1.0
CZ2 A:TRP212 4.8 25.5 1.0
CD1 A:TYR239 4.8 25.1 1.0
CZ A:TYR213 4.9 27.7 1.0
CB A:PRO216 4.9 27.8 1.0
CE2 A:TYR239 5.0 24.4 1.0

Reference:

M.C.Lewis, T.L.Poulos. Selective Anti-Mrsa Inhibitors Targeting Nitric Oxide Synthase To Be Published.
Page generated: Sat Jul 12 21:36:45 2025

Last articles

Na in 1VQ7
Na in 1VQ5
Na in 1VQ6
Na in 1VQ4
Na in 1VI6
Na in 1VKG
Na in 1VMJ
Na in 1VMH
Na in 1VMF
Na in 1VLM
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy