Chlorine in PDB 6xte: Human Karyopherin RANBP5 (Isoform-1)

The structure of Human Karyopherin RANBP5 (Isoform-1), PDB code: 6xte was solved by C.Swale, A.A.Mccarthy, R.W.H.Ruigrok, T.Crepin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	78.49 / 2.27
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	87.091, 96.313, 156.979, 90.00, 90.00, 90.00
R / Rfree (%)	19.9 / 26

The structure of Human Karyopherin RANBP5 (Isoform-1) also contains other interesting chemical elements:

Nickel

(Ni)

2 atoms

The binding sites of Chlorine atom in the Human Karyopherin RANBP5 (Isoform-1) (pdb code 6xte). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Karyopherin RANBP5 (Isoform-1), PDB code: 6xte:

Chlorine binding site 1 out of 1 in the Human Karyopherin RANBP5 (Isoform-1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Karyopherin RANBP5 (Isoform-1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1203 b:90.8 occ:1.00 NE2 A:HIS394 3.4 53.3 1.0 NH2 A:ARG432 3.5 67.5 1.0 NE A:ARG432 3.8 63.7 1.0 CD2 A:TYR435 4.0 61.1 1.0 CZ A:ARG432 4.1 66.4 1.0 CB A:TYR435 4.3 56.8 1.0 CD2 A:HIS394 4.3 52.3 1.0 CE1 A:HIS394 4.4 52.9 1.0 O A:ARG432 4.4 57.2 1.0 CG A:TYR435 4.7 59.4 1.0 CB A:ARG432 4.9 57.1 1.0 NE2 A:HIS479 4.9 63.3 1.0

C.Swale, B.Da Costa, L.Sedano, F.Garzoni, A.A.Mccarthy, I.Berger, C.Bieniossek, R.W.H.Ruigrok, B.Delmas, T.Crepin. X-Ray Structure of the Human Karyopherin RANBP5, An Essential Factor For Influenza Polymerase Nuclear Trafficking. J.Mol.Biol. 2020.
ISSN: ESSN 1089-8638
PubMed: 32222384
DOI: 10.1016/J.JMB.2020.03.021