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Atomistry » Chlorine » PDB 6yyc-6zbo » 6z45 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 6yyc-6zbo » 6z45 » |
Chlorine in PDB 6z45: CDK9-Cyclin-T1 Complex Bound By Compound 24Enzymatic activity of CDK9-Cyclin-T1 Complex Bound By Compound 24
All present enzymatic activity of CDK9-Cyclin-T1 Complex Bound By Compound 24:
2.7.11.22; 2.7.11.23; Protein crystallography data
The structure of CDK9-Cyclin-T1 Complex Bound By Compound 24, PDB code: 6z45
was solved by
A.Ferguson,
G.W.Collie,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the CDK9-Cyclin-T1 Complex Bound By Compound 24
(pdb code 6z45). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the CDK9-Cyclin-T1 Complex Bound By Compound 24, PDB code: 6z45: Chlorine binding site 1 out of 1 in 6z45Go back to![]() ![]()
Chlorine binding site 1 out
of 1 in the CDK9-Cyclin-T1 Complex Bound By Compound 24
![]() Mono view ![]() Stereo pair view
Reference:
B.Barlaam,
R.Casella,
J.Cidado,
C.Cook,
C.De Savi,
A.Dishington,
C.S.Donald,
L.Drew,
A.D.Ferguson,
D.Ferguson,
S.Glossop,
T.Grebe,
C.Gu,
S.Hande,
J.Hawkins,
A.W.Hird,
J.Holmes,
J.Horstick,
Y.Jiang,
M.L.Lamb,
T.M.Mcguire,
J.E.Moore,
N.O'connell,
A.Pike,
K.G.Pike,
T.Proia,
B.Roberts,
M.San Martin,
U.Sarkar,
W.Shao,
D.Stead,
N.Sumner,
K.Thakur,
M.M.Vasbinder,
J.G.Varnes,
J.Wang,
L.Wang,
D.Wu,
L.Wu,
B.Yang,
T.Yao.
Discovery of AZD4573, A Potent and Selective Inhibitor of CDK9 That Enables Short Duration of Target Engagement For the Treatment of Hematological Malignancies. J.Med.Chem. 2020.
Page generated: Mon Jul 29 17:56:47 2024
ISSN: ISSN 0022-2623 PubMed: 33306391 DOI: 10.1021/ACS.JMEDCHEM.0C01754 |
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