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Atomistry » Chlorine » PDB 6zyz-7a8p » 7a12 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 6zyz-7a8p » 7a12 » |
Chlorine in PDB 7a12: Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GW557358X (Compound 9)Enzymatic activity of Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GW557358X (Compound 9)
All present enzymatic activity of Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GW557358X (Compound 9):
3.4.11.18; Protein crystallography data
The structure of Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GW557358X (Compound 9), PDB code: 7a12
was solved by
J.H.Thorpe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7a12:
The structure of Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GW557358X (Compound 9) also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GW557358X (Compound 9)
(pdb code 7a12). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GW557358X (Compound 9), PDB code: 7a12: Chlorine binding site 1 out of 1 in 7a12Go back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure of Human Methionine Aminopeptidase-2 in Complex with An Inhibitor GW557358X (Compound 9)
![]() Mono view ![]() Stereo pair view
Reference:
D.J.Hirst,
M.Brandt,
G.Bruton,
E.Christodoulou,
L.Cutler,
N.Deeks,
J.D.Goodacre,
T.Jack,
M.Lindon,
A.Miah,
K.Page,
N.Parr,
L.Shukla,
M.Sims,
P.Thomas,
J.Thorpe,
D.S.Holmes.
Structure-Based Optimisation of Orally Active & Reversible Metap-2 Inhibitors Maintaining A Tight 'Molecular Budget'. Bioorg.Med.Chem.Lett. V. 30 27533 2020.
Page generated: Mon Jul 29 18:17:53 2024
ISSN: ESSN 1464-3405 PubMed: 32919012 DOI: 10.1016/J.BMCL.2020.127533 |
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