Chlorine in PDB 7a5v: Cryoem Structure of A Human Gamma-Aminobutyric Acid Receptor, the Gaba(A)R-BETA3 Homopentamer, in Complex with Histamine and Megabody MB25 in Lipid Nanodisc

The binding sites of Chlorine atom in the Cryoem Structure of A Human Gamma-Aminobutyric Acid Receptor, the Gaba(A)R-BETA3 Homopentamer, in Complex with Histamine and Megabody MB25 in Lipid Nanodisc (pdb code 7a5v). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Cryoem Structure of A Human Gamma-Aminobutyric Acid Receptor, the Gaba(A)R-BETA3 Homopentamer, in Complex with Histamine and Megabody MB25 in Lipid Nanodisc, PDB code: 7a5v:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Cryoem Structure of A Human Gamma-Aminobutyric Acid Receptor, the Gaba(A)R-BETA3 Homopentamer, in Complex with Histamine and Megabody MB25 in Lipid Nanodisc


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryoem Structure of A Human Gamma-Aminobutyric Acid Receptor, the Gaba(A)R-BETA3 Homopentamer, in Complex with Histamine and Megabody MB25 in Lipid Nanodisc within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl5409 b:95.5 occ:0.20 O A:HOH5657 3.7 38.6 1.0 CB A:ALA248 4.0 27.7 1.0

Chlorine binding site 2 out of 2 in the Cryoem Structure of A Human Gamma-Aminobutyric Acid Receptor, the Gaba(A)R-BETA3 Homopentamer, in Complex with Histamine and Megabody MB25 in Lipid Nanodisc


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Cryoem Structure of A Human Gamma-Aminobutyric Acid Receptor, the Gaba(A)R-BETA3 Homopentamer, in Complex with Histamine and Megabody MB25 in Lipid Nanodisc within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl5410 b:39.0 occ:1.00 O A:HOH5607 2.5 37.0 0.5 O A:HOH5667 2.8 28.6 1.0 O A:HOH5692 2.9 63.6 1.0 ND1 A:HIS107 3.7 25.1 1.0 N A:GLY108 3.8 17.2 1.0 CE2 A:PHE105 3.8 21.9 1.0 CA A:HIS107 3.9 16.4 1.0 CB A:HIS107 4.2 17.5 1.0 O A:HOH5540 4.2 34.6 1.0 CG A:HIS107 4.2 18.5 1.0 CD2 A:PHE105 4.4 21.2 1.0 C A:HIS107 4.4 15.8 1.0 CE1 A:HIS107 4.6 24.6 1.0 CZ A:PHE105 4.8 22.6 1.0 CA A:GLY108 4.9 17.3 1.0 N A:VAL109 5.0 15.4 1.0

T.Nakane, A.Kotecha, A.Sente, G.Mcmullan, S.Masiulis, P.M.G.E.Brown, I.T.Grigoras, L.Malinauskaite, T.Malinauskas, J.Miehling, T.Uchanski, L.Yu, D.Karia, E.V.Pechnikova, E.De Jong, J.Keizer, M.Bischoff, J.Mccormack, P.Tiemeijer, S.W.Hardwick, D.Y.Chirgadze, G.Murshudov, A.R.Aricescu, S.H.W.Scheres. Single-Particle Cryo-Em at Atomic Resolution. Nature V. 587 152 2020.
ISSN: ESSN 1476-4687
PubMed: 33087931
DOI: 10.1038/S41586-020-2829-0