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Atomistry » Chlorine » PDB 7a8s-7aj5 » 7ab1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 7a8s-7aj5 » 7ab1 » |
Chlorine in PDB 7ab1: Crystal Structure of Mertk Kinase Domain in Complex with GilteritinibEnzymatic activity of Crystal Structure of Mertk Kinase Domain in Complex with Gilteritinib
All present enzymatic activity of Crystal Structure of Mertk Kinase Domain in Complex with Gilteritinib:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of Mertk Kinase Domain in Complex with Gilteritinib, PDB code: 7ab1
was solved by
A.Pflug,
M.Schimpl,
W.Mccoull,
J.W.M.Nissink,
R.C.Overman,
P.B.Rawlins,
C.Truman,
E.Underwood,
J.Warwicker,
J.Winter-Holt,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Mertk Kinase Domain in Complex with Gilteritinib
(pdb code 7ab1). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Mertk Kinase Domain in Complex with Gilteritinib, PDB code: 7ab1: Jump to Chlorine binding site number: 1; 2; 3; 4; Chlorine binding site 1 out of 4 in 7ab1Go back to![]() ![]()
Chlorine binding site 1 out
of 4 in the Crystal Structure of Mertk Kinase Domain in Complex with Gilteritinib
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 4 in 7ab1Go back to![]() ![]()
Chlorine binding site 2 out
of 4 in the Crystal Structure of Mertk Kinase Domain in Complex with Gilteritinib
![]() Mono view ![]() Stereo pair view
Chlorine binding site 3 out of 4 in 7ab1Go back to![]() ![]()
Chlorine binding site 3 out
of 4 in the Crystal Structure of Mertk Kinase Domain in Complex with Gilteritinib
![]() Mono view ![]() Stereo pair view
Chlorine binding site 4 out of 4 in 7ab1Go back to![]() ![]()
Chlorine binding site 4 out
of 4 in the Crystal Structure of Mertk Kinase Domain in Complex with Gilteritinib
![]() Mono view ![]() Stereo pair view
Reference:
A.Pflug,
M.Schimpl,
J.W.M.Nissink,
R.C.Overman,
P.B.Rawlins,
C.Truman,
E.Underwood,
J.Warwicker,
J.Winter-Holt,
W.Mccoull.
A-Loop Interactions in Mer Tyrosine Kinase Give Rise to Inhibitors with Two-Step Mechanism and Long Residence Time of Binding. Biochem.J. V. 477 4443 2020.
Page generated: Mon Jul 29 18:25:47 2024
ISSN: ESSN 1470-8728 PubMed: 33119085 DOI: 10.1042/BCJ20200735 |
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