Chlorine in PDB 7c0s: Crystal Structure of A Dinucleotide-Binding Protein (F79A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II)

The structure of Crystal Structure of A Dinucleotide-Binding Protein (F79A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II), PDB code: 7c0s was solved by S.P.Kanaujia, M.Chandravanshi, R.Samanta, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	60.56 / 1.85
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	66.539, 58.36, 123.82, 90, 94.81, 90
R / Rfree (%)	20.5 / 24

The binding sites of Chlorine atom in the Crystal Structure of A Dinucleotide-Binding Protein (F79A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II) (pdb code 7c0s). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of A Dinucleotide-Binding Protein (F79A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II), PDB code: 7c0s:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of A Dinucleotide-Binding Protein (F79A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of A Dinucleotide-Binding Protein (F79A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:36.4 occ:1.00 O A:HOH776 2.3 23.2 1.0 N A:ALA174 3.0 13.0 1.0 O A:HOH813 3.2 15.4 1.0 O A:ARG360 3.2 13.8 1.0 CB A:ALA174 3.6 12.8 1.0 CA A:GLY365 3.6 17.6 1.0 CB A:ASP173 3.6 16.1 1.0 CA A:ASP173 3.7 14.9 1.0 C A:ASP173 3.8 14.0 1.0 CD1 A:PHE361 3.8 16.9 1.0 CA A:ALA174 3.9 13.3 1.0 O A:HOH945 4.0 29.6 1.0 CA A:PHE361 4.0 16.1 1.0 C A:ARG360 4.1 14.7 1.0 N A:GLY365 4.3 16.9 1.0 CE1 A:PHE361 4.3 16.7 1.0 O A:HOH610 4.4 45.6 1.0 NZ A:LYS369 4.4 23.7 1.0 N A:PHE361 4.4 14.9 1.0 NH1 A:ARG360 4.5 15.6 1.0 O A:PHE361 4.5 18.1 1.0 CG A:PHE361 4.6 17.0 1.0 CG A:ASP173 4.7 16.1 1.0 C A:PHE361 4.8 17.7 1.0 CB A:PHE361 4.8 16.9 1.0 C A:GLY365 4.8 17.8 1.0 N A:SER175 4.9 12.8 1.0 C A:ALA174 5.0 12.6 1.0 O A:HOH912 5.0 42.5 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of A Dinucleotide-Binding Protein (F79A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of A Dinucleotide-Binding Protein (F79A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl501 b:37.7 occ:1.00 O B:HOH711 2.6 30.4 1.0 N B:ALA174 3.0 13.7 1.0 O B:ARG360 3.0 16.6 1.0 O B:HOH767 3.2 16.4 1.0 CB B:ALA174 3.5 14.0 1.0 CA B:GLY365 3.5 18.5 1.0 CB B:ASP173 3.7 17.6 1.0 CA B:ASP173 3.8 16.2 1.0 CA B:ALA174 3.8 14.2 1.0 C B:ASP173 3.9 14.6 1.0 CD1 B:PHE361 3.9 18.2 1.0 O B:HOH834 3.9 33.9 1.0 CA B:PHE361 4.0 18.3 1.0 C B:ARG360 4.0 15.8 1.0 N B:GLY365 4.2 17.2 1.0 O B:HOH916 4.2 28.5 1.0 N B:PHE361 4.3 17.1 1.0 CE1 B:PHE361 4.4 17.4 1.0 NH1 B:ARG360 4.4 16.3 1.0 NZ B:LYS369 4.4 28.3 1.0 O B:PHE361 4.5 20.7 1.0 CG B:PHE361 4.6 18.2 1.0 C B:PHE361 4.8 19.6 1.0 CB B:PHE361 4.8 18.9 1.0 C B:GLY365 4.8 18.7 1.0 CG B:ASP173 4.8 17.7 1.0 C B:ALA174 4.9 13.3 1.0 N B:SER175 5.0 13.1 1.0

M.Chandravanshi, R.Samanta, S.P.Kanaujia. Structural and Thermodynamic Insights Into the Novel Dinucleotide-Binding Protein of Abc Transporter Unveils Its Moonlighting Function. Febs J. 2021.
ISSN: ISSN 1742-464X
PubMed: 33599038
DOI: 10.1111/FEBS.15774