Chlorine in PDB 7c3y: Crystal Structure of the N-Terminal Domain of Human Mdmx Protein in Complex with NUTLIN3A

The structure of Crystal Structure of the N-Terminal Domain of Human Mdmx Protein in Complex with NUTLIN3A, PDB code: 7c3y was solved by Z.D.Su, X.Y.Cheng, B.L.Zhang, Z.K.Kuang, J.Yang, Z.C.Li, J.P.Yu, Z.T.Zhao, C.Z.Cao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.15 / 1.63
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	47.552, 47.552, 90.676, 90.00, 90.00, 90.00
R / Rfree (%)	20 / 22.7

The binding sites of Chlorine atom in the Crystal Structure of the N-Terminal Domain of Human Mdmx Protein in Complex with NUTLIN3A (pdb code 7c3y). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the N-Terminal Domain of Human Mdmx Protein in Complex with NUTLIN3A, PDB code: 7c3y:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of the N-Terminal Domain of Human Mdmx Protein in Complex with NUTLIN3A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the N-Terminal Domain of Human Mdmx Protein in Complex with NUTLIN3A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl202 b:32.8 occ:1.00 CL1 A:NUT202 0.0 32.8 1.0 C22 A:NUT202 1.7 32.4 1.0 C21 A:NUT202 2.7 31.6 1.0 C23 A:NUT202 2.7 32.1 1.0 HD21 A:LEU97 2.8 40.5 1.0 H25 A:NUT202 2.8 31.6 1.0 H24 A:NUT202 2.8 32.1 1.0 HB3 A:LEU55 2.9 27.7 1.0 HD12 A:ILE59 3.0 28.3 1.0 HD22 A:LEU97 3.1 40.5 1.0 HZ A:PHE89 3.1 37.9 1.0 HD11 A:ILE59 3.2 28.3 1.0 CD2 A:LEU97 3.4 40.5 1.0 CD1 A:ILE59 3.5 28.3 1.0 HD13 A:LEU97 3.6 40.0 1.0 HD13 A:LEU55 3.6 32.8 1.0 HD12 A:LEU97 3.8 40.0 1.0 CB A:LEU55 3.8 27.7 1.0 HD13 A:ILE59 3.9 28.3 1.0 HB2 A:LEU55 3.9 27.7 1.0 C20 A:NUT202 4.0 33.2 1.0 C24 A:NUT202 4.0 31.5 1.0 CZ A:PHE89 4.0 37.9 1.0 CD1 A:LEU97 4.0 40.0 1.0 HD23 A:LEU97 4.1 40.5 1.0 HD21 A:LEU55 4.2 30.6 1.0 HE1 A:PHE89 4.3 36.5 1.0 CG A:LEU97 4.3 41.0 1.0 HD22 A:LEU80 4.4 33.3 1.0 CD1 A:LEU55 4.4 32.8 1.0 C19 A:NUT202 4.5 31.3 1.0 C A:LEU55 4.5 25.5 1.0 HE1 A:MET52 4.6 42.5 1.0 HD11 A:LEU55 4.6 32.8 1.0 CE1 A:PHE89 4.6 36.5 1.0 CG A:LEU55 4.6 28.0 1.0 HE3 A:MET52 4.7 42.5 1.0 H26 A:NUT202 4.7 33.2 1.0 O A:LEU55 4.7 28.6 1.0 HA2 A:GLY56 4.7 28.0 1.0 H23 A:NUT202 4.7 31.5 1.0 HG13 A:ILE59 4.7 26.1 1.0 HB2 A:LEU97 4.8 34.3 1.0 CG1 A:ILE59 4.8 26.1 1.0 N A:GLY56 4.8 27.1 1.0 CA A:LEU55 4.8 26.8 1.0 HD12 A:LEU80 4.9 29.7 1.0 CD2 A:LEU55 4.9 30.6 1.0 HD11 A:LEU97 5.0 40.0 1.0 HE2 A:PHE89 5.0 37.0 1.0 CE2 A:PHE89 5.0 37.0 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of the N-Terminal Domain of Human Mdmx Protein in Complex with NUTLIN3A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the N-Terminal Domain of Human Mdmx Protein in Complex with NUTLIN3A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl202 b:41.8 occ:1.00 CL A:NUT202 0.0 41.8 1.0 C15 A:NUT202 1.7 38.5 1.0 C16 A:NUT202 2.6 35.1 1.0 C14 A:NUT202 2.7 37.0 1.0 H31 A:NUT202 2.7 35.1 1.0 H32 A:NUT202 2.8 37.0 1.0 HB2 A:PRO94 3.0 44.9 1.0 HD23 A:LEU97 3.0 40.5 1.0 HE2 A:TYR98 3.3 36.7 1.0 HE2 A:MET52 3.5 42.5 1.0 HG3 A:PRO94 3.6 43.1 1.0 CB A:PRO94 3.7 44.9 1.0 HB3 A:PRO94 3.7 44.9 1.0 CE2 A:TYR98 3.7 36.7 1.0 HG2 A:PRO94 3.9 43.1 1.0 CD2 A:LEU97 3.9 40.5 1.0 CG A:PRO94 3.9 43.1 1.0 HE1 A:MET52 3.9 42.5 1.0 C17 A:NUT202 3.9 34.1 1.0 C13 A:NUT202 4.0 36.4 1.0 HD22 A:LEU97 4.1 40.5 1.0 HG A:LEU97 4.1 41.0 1.0 CE A:MET52 4.1 42.5 1.0 HB3 A:LEU97 4.1 34.3 1.0 HD2 A:TYR98 4.3 31.7 1.0 CD2 A:TYR98 4.3 31.7 1.0 CZ A:TYR98 4.4 38.7 1.0 CG A:LEU97 4.5 41.0 1.0 C12 A:NUT202 4.5 31.4 1.0 OH A:TYR98 4.5 46.1 1.0 HD21 A:LEU97 4.6 40.5 1.0 HE3 A:MET52 4.6 42.5 1.0 H30 A:NUT202 4.7 34.1 1.0 H33 A:NUT202 4.7 36.4 1.0 CB A:LEU97 4.8 34.3 1.0 O A:PRO94 5.0 34.3 1.0

Z.D.Su, X.Y.Cheng, B.L.Zhang, Z.K.Kuang, J.Yang, Z.C.Li, J.P.Yu, C.Z.Cao, Z.T.Zhao. Crystal Structure of the N-Terminal Domain of Human Mdmx Protein in Complex with NUTLIN3A To Be Published.