Chlorine in PDB 7ckr: Cryo-Em Structure of the Human MCT1/Basigin-2 Complex in the Presence of Anti-Cancer Drug Candidate Bay-8002 in the Outward-Open Conformation.

The binding sites of Chlorine atom in the Cryo-Em Structure of the Human MCT1/Basigin-2 Complex in the Presence of Anti-Cancer Drug Candidate Bay-8002 in the Outward-Open Conformation. (pdb code 7ckr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of the Human MCT1/Basigin-2 Complex in the Presence of Anti-Cancer Drug Candidate Bay-8002 in the Outward-Open Conformation., PDB code: 7ckr:

Chlorine binding site 1 out of 1 in the Cryo-Em Structure of the Human MCT1/Basigin-2 Complex in the Presence of Anti-Cancer Drug Candidate Bay-8002 in the Outward-Open Conformation.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of the Human MCT1/Basigin-2 Complex in the Presence of Anti-Cancer Drug Candidate Bay-8002 in the Outward-Open Conformation. within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl601 b:70.6 occ:1.00 CL1 A:G5O601 0.0 70.6 1.0 C13 A:G5O601 1.8 70.6 1.0 C14 A:G5O601 2.7 70.6 1.0 C12 A:G5O601 2.9 70.6 1.0 O19 A:G5O601 3.0 70.6 1.0 C17 A:G5O601 3.0 70.6 1.0 CD1 A:TYR34 3.4 69.1 1.0 CA A:TYR34 3.9 69.1 1.0 CE1 A:TYR34 4.0 69.1 1.0 CD1 A:LEU66 4.0 68.2 1.0 C11 A:G5O601 4.1 70.6 1.0 N18 A:G5O601 4.1 70.6 1.0 C15 A:G5O601 4.1 70.6 1.0 O A:SER33 4.2 68.4 1.0 SD A:MET69 4.2 68.7 1.0 CE A:MET69 4.2 68.7 1.0 O A:TYR34 4.3 69.1 1.0 C A:TYR34 4.3 69.1 1.0 CG A:PRO37 4.4 69.6 1.0 CG A:TYR34 4.4 69.1 1.0 C10 A:G5O601 4.6 70.6 1.0 CB A:TYR34 4.6 69.1 1.0 N A:TYR34 4.7 69.1 1.0 C A:SER33 4.7 68.4 1.0 CE1 A:TYR70 4.7 68.9 1.0 CD A:PRO37 4.7 69.6 1.0 OH A:TYR70 4.9 68.9 1.0

N.Wang, X.Jiang, S.Zhang, A.Zhu, Y.Yuan, J.Lei, C.Yan. Structural Basis of Human Monocarboxylate Transporter 1 Inhibition By Anti-Cancer Drug Candidates To Be Published.