Atomistry » Chlorine » PDB 7f6q-7fgy » 7f9a
Atomistry »
  Chlorine »
    PDB 7f6q-7fgy »
      7f9a »

Chlorine in PDB 7f9a: Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L97

Enzymatic activity of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L97

All present enzymatic activity of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L97:
6.1.1.15; 6.1.1.17;

Protein crystallography data

The structure of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L97, PDB code: 7f9a was solved by Y.Manickam, N.Malhotra, A.Sharma, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 59.93 / 2.00
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 70.74, 105.92, 145.38, 90, 90, 90
R / Rfree (%) 19.5 / 24.2

Other elements in 7f9a:

The structure of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L97 also contains other interesting chemical elements:

Calcium (Ca) 10 atoms
Fluorine (F) 2 atoms
Zinc (Zn) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L97 (pdb code 7f9a). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L97, PDB code: 7f9a:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in 7f9a

Go back to Chlorine Binding Sites List in 7f9a
Chlorine binding site 1 out of 3 in the Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L97


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L97 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1909

b:57.9
occ:0.82
 N A:GLU1017 2.9 62.4 1.0
N A:ALA1018 3.2 49.8 1.0
NE2 A:GLN1030 3.4 58.0 1.0
CE A:LYS1034 3.4 66.5 1.0
CA A:LEU1016 3.7 66.4 1.0
C A:LEU1016 3.8 65.7 1.0
CG A:GLN1030 3.8 48.8 1.0
CD1 A:LEU1016 3.8 60.2 1.0
CA A:GLU1017 3.8 67.0 1.0
CB A:GLN1030 3.9 45.7 1.0
CB A:ALA1018 3.9 46.8 1.0
C A:GLU1017 4.0 61.7 1.0
CG A:LEU1016 4.0 58.2 1.0
CD A:GLN1030 4.1 58.4 1.0
CA A:ALA1018 4.2 50.4 1.0
CB A:GLU1017 4.3 68.5 1.0
NZ A:LYS1034 4.3 72.0 1.0
CD A:LYS1034 4.3 48.2 1.0
CB A:LEU1016 4.4 56.2 1.0
O A:GLY1015 4.4 92.5 1.0
N A:LEU1016 4.8 70.6 1.0
CG A:GLU1017 5.0 75.8 1.0
O A:LEU1016 5.0 76.4 1.0

Chlorine binding site 2 out of 3 in 7f9a

Go back to Chlorine Binding Sites List in 7f9a
Chlorine binding site 2 out of 3 in the Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L97


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L97 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1910

b:97.0
occ:1.00
 NE2 A:HIS1423 3.8 73.8 1.0
CD2 A:HIS1423 4.6 72.9 1.0
O A:SER1439 4.8 84.8 1.0
CE1 A:HIS1423 4.9 74.9 1.0

Chlorine binding site 3 out of 3 in 7f9a

Go back to Chlorine Binding Sites List in 7f9a
Chlorine binding site 3 out of 3 in the Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L97


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Homo Sapiens Prolyl-Trna Synthetase (Hsprs) in Complex with L-Proline and Compound L97 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1912

b:58.5
occ:0.71
 NE1 B:TRP1153 3.4 45.8 1.0
N A:ALA1113 3.5 65.4 1.0
CE1 B:PHE1155 3.5 60.1 1.0
CD2 A:LEU1112 3.7 61.9 1.0
CB A:ALA1113 3.9 69.7 1.0
CD1 B:PHE1155 4.1 55.8 1.0
CE2 B:TRP1153 4.1 50.7 1.0
CZ2 B:TRP1153 4.2 53.7 1.0
CB A:LEU1112 4.2 50.4 1.0
CA A:LEU1112 4.2 70.8 1.0
CA A:ALA1113 4.3 75.2 1.0
C A:LEU1112 4.4 71.5 1.0
CG A:LEU1112 4.5 56.0 1.0
CD1 B:TRP1153 4.5 55.6 1.0
CZ B:PHE1155 4.6 56.7 1.0

Reference:

N.Malhotra, Y.Manickam, A.Sharma. Hsprs with Atp Binding Pocket Inhibitor To Be Published.
Page generated: Sun Jul 13 00:33:32 2025

Last articles

Fe in 9O8U
Fe in 9N5V
Fe in 9NSE
Fe in 9NQU
Fe in 9NP6
Fe in 9NH3
Fe in 9NEA
Fe in 9NE9
Fe in 9NE8
Fe in 9NE7
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy