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Chlorine in PDB 7fcy: Crystal Structure of M.Tuberculosis Imidazole Glycerol Phosphate Dehydratase in Complex with An Inhibitor

Enzymatic activity of Crystal Structure of M.Tuberculosis Imidazole Glycerol Phosphate Dehydratase in Complex with An Inhibitor

All present enzymatic activity of Crystal Structure of M.Tuberculosis Imidazole Glycerol Phosphate Dehydratase in Complex with An Inhibitor:
4.2.1.19;

Protein crystallography data

The structure of Crystal Structure of M.Tuberculosis Imidazole Glycerol Phosphate Dehydratase in Complex with An Inhibitor, PDB code: 7fcy was solved by S.Tiwari, R.K.Pal, B.K.Biswal, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 34.13 / 1.85
Space group P 4 3 2
Cell size a, b, c (Å), α, β, γ (°) 113.116, 113.116, 113.116, 90, 90, 90
R / Rfree (%) 15.5 / 18.4

Other elements in 7fcy:

The structure of Crystal Structure of M.Tuberculosis Imidazole Glycerol Phosphate Dehydratase in Complex with An Inhibitor also contains other interesting chemical elements:

Manganese (Mn) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of M.Tuberculosis Imidazole Glycerol Phosphate Dehydratase in Complex with An Inhibitor (pdb code 7fcy). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of M.Tuberculosis Imidazole Glycerol Phosphate Dehydratase in Complex with An Inhibitor, PDB code: 7fcy:

Chlorine binding site 1 out of 1 in 7fcy

Go back to Chlorine Binding Sites List in 7fcy
Chlorine binding site 1 out of 1 in the Crystal Structure of M.Tuberculosis Imidazole Glycerol Phosphate Dehydratase in Complex with An Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of M.Tuberculosis Imidazole Glycerol Phosphate Dehydratase in Complex with An Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl305

b:25.9
occ:0.33
NH2 A:ARG168 3.3 26.1 1.0
NH1 A:ARG168 3.7 28.5 1.0
CZ A:ARG168 3.9 26.0 1.0
CZ A:PHE104 3.9 19.4 1.0
CE1 A:PHE104 4.4 18.4 1.0
CD1 A:LEU170 4.5 20.7 0.5
CD1 A:LEU170 5.0 16.6 0.5

Reference:

S.Tiwari, R.K.Pal, B.K.Biswal. Crystal Structure of M.Tuberculosis Imidazole Glycerol Phosphate Dehydratase in Complex with An Inhibitor To Be Published.
Page generated: Sun Jul 13 00:36:01 2025

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