Chlorine in PDB 7g1p: Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 6-Chloro-5-Fluoro-1H-Benzimidazole

The structure of Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 6-Chloro-5-Fluoro-1H-Benzimidazole, PDB code: 7g1p was solved by A.Ehler, J.Benz, U.Obst, M.G.Rudolph, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.72 / 1.28
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	32.158, 52.964, 72.24, 90, 90, 90
R / Rfree (%)	17.6 / 24.2

The structure of Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 6-Chloro-5-Fluoro-1H-Benzimidazole also contains other interesting chemical elements:

Fluorine

(F)

1 atom

The binding sites of Chlorine atom in the Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 6-Chloro-5-Fluoro-1H-Benzimidazole (pdb code 7g1p). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 6-Chloro-5-Fluoro-1H-Benzimidazole, PDB code: 7g1p:

Chlorine binding site 1 out of 1 in the Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 6-Chloro-5-Fluoro-1H-Benzimidazole


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human FABP4 Binding Site Mutated to That of FABP5 in Complex with 6-Chloro-5-Fluoro-1H-Benzimidazole within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl201 b:30.6 occ:1.00 CL11 A:WPK201 0.0 30.6 1.0 C9 A:WPK201 1.7 19.8 1.0 C5 A:WPK201 2.6 20.6 1.0 C7 A:WPK201 2.7 21.4 1.0 F10 A:WPK201 3.0 28.4 1.0 O A:HOH349 3.2 21.7 1.0 O A:GLY33 3.4 20.1 1.0 NH2 A:ARG126 3.7 18.5 1.0 CE2 A:PHE16 3.7 14.2 1.0 CB A:ALA36 3.7 21.4 1.0 CA A:GLY33 3.9 18.3 1.0 C2 A:WPK201 3.9 19.8 1.0 C3 A:WPK201 3.9 20.1 1.0 CZ A:PHE16 4.0 14.4 1.0 C A:GLY33 4.1 16.8 1.0 C11 A:MYR202 4.2 34.6 1.0 CG A:PRO38 4.3 21.1 1.0 O A:HOH327 4.4 30.7 1.0 C1 A:WPK201 4.4 21.1 1.0 C13 A:MYR202 4.5 38.2 1.0 CZ A:ARG126 4.6 13.7 1.0 CD A:PRO38 4.6 13.8 1.0 C12 A:MYR202 4.6 34.5 1.0 NH1 A:ARG126 4.8 15.1 1.0 CD2 A:PHE16 4.8 13.1 1.0 CA A:ALA36 4.9 21.4 1.0 O A:ALA36 4.9 21.9 1.0

U.Obst, C.Magnone, B.Kuhn, M.G.Rudolph. Crystal Structure of A Human FABP4 Binding Site Mutated to That of FABP5 Complex To Be Published.