Chlorine in PDB 7jhn: Structure of Human Beta 1,3-N-Acetylglucosaminyltransferase 2 with Udp and Trisaccharide Glcnac-BETA1-3GAL-BETA1-4GLCNAC

Enzymatic activity of Structure of Human Beta 1,3-N-Acetylglucosaminyltransferase 2 with Udp and Trisaccharide Glcnac-BETA1-3GAL-BETA1-4GLCNAC

All present enzymatic activity of Structure of Human Beta 1,3-N-Acetylglucosaminyltransferase 2 with Udp and Trisaccharide Glcnac-BETA1-3GAL-BETA1-4GLCNAC:
2.4.1.149;

Protein crystallography data

The structure of Structure of Human Beta 1,3-N-Acetylglucosaminyltransferase 2 with Udp and Trisaccharide Glcnac-BETA1-3GAL-BETA1-4GLCNAC, PDB code: 7jhn was solved by Y.Hao, X.Huang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	39.89 / 2.20
*Space group*	C 1 2 1
*Cell size a, b, c (Å), α, β, γ (°)*	82.916, 76.865, 66.786, 90.00, 105.82, 90.00
*R / R_free (%)*	19.6 / 25.5

Other elements in 7jhn:

The structure of Structure of Human Beta 1,3-N-Acetylglucosaminyltransferase 2 with Udp and Trisaccharide Glcnac-BETA1-3GAL-BETA1-4GLCNAC also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of Human Beta 1,3-N-Acetylglucosaminyltransferase 2 with Udp and Trisaccharide Glcnac-BETA1-3GAL-BETA1-4GLCNAC (pdb code 7jhn). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of Human Beta 1,3-N-Acetylglucosaminyltransferase 2 with Udp and Trisaccharide Glcnac-BETA1-3GAL-BETA1-4GLCNAC, PDB code: 7jhn:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 7jhn

Go back to

Chlorine Binding Sites List in 7jhn

Chlorine binding site 1 out of 2 in the Structure of Human Beta 1,3-N-Acetylglucosaminyltransferase 2 with Udp and Trisaccharide Glcnac-BETA1-3GAL-BETA1-4GLCNAC

Mono view

Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Human Beta 1,3-N-Acetylglucosaminyltransferase 2 with Udp and Trisaccharide Glcnac-BETA1-3GAL-BETA1-4GLCNAC within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Cl404 b:65.2 occ:1.00	O	A:HOH593	3.2	45.8	1.0
	ND1	A:HIS205	3.8	34.7	1.0
	NH2	A:ARG178	3.8	27.4	1.0
	CE1	A:HIS205	4.7	27.0	1.0
	CG	A:HIS205	4.7	34.0	1.0
	CD	A:ARG162	4.7	28.7	1.0
	CB	A:HIS205	4.7	37.7	1.0
	O	A:HIS205	4.8	57.7	1.0
	CA	A:HIS205	4.8	35.7	1.0
	CZ	A:ARG178	4.9	24.0	1.0

Chlorine binding site 2 out of 2 in 7jhn

Go back to

Chlorine Binding Sites List in 7jhn

Chlorine binding site 2 out of 2 in the Structure of Human Beta 1,3-N-Acetylglucosaminyltransferase 2 with Udp and Trisaccharide Glcnac-BETA1-3GAL-BETA1-4GLCNAC

Mono view

Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Human Beta 1,3-N-Acetylglucosaminyltransferase 2 with Udp and Trisaccharide Glcnac-BETA1-3GAL-BETA1-4GLCNAC within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Cl405 b:69.7 occ:1.00	O	A:HOH599	3.0	41.2	1.0
	O	A:HOH585	3.4	20.1	1.0
	O	A:HOH600	4.0	25.9	1.0
	CG	A:LYS379	4.3	23.9	1.0
	O	A:HOH604	4.4	38.3	0.5
	NE	A:ARG157	4.4	28.8	1.0
	NH2	A:ARG157	4.4	28.7	1.0
	CE	A:LYS379	4.5	59.5	1.0
	CD	A:PRO380	4.5	14.8	1.0
	CZ	A:ARG157	4.7	22.1	1.0
	CD	A:LYS379	4.8	31.5	1.0
	CB	A:LYS379	5.0	11.5	1.0

Reference:

Y.Hao, A.Crequer-Grandhomme, N.Javier, A.Singh, H.Chen, P.Manzanillo, M.C.Lo, X.Huang. Structures and Mechanism of Human Glycosyltransferase Beta 1,3-N-Acetylglucosaminyltransferase 2 (B3GNT2), An Important Player in Immune Homeostasis. J.Biol.Chem. 2020.
ISSN: ESSN 1083-351X
PubMed: 33158990
DOI: 10.1074/JBC.RA120.015306

Page generated: Sun Jul 13 02:56:16 2025

Last articles

Mg in 5G0R
Mg in 5G5V
Mg in 5G3T
Mg in 5G5T
Mg in 5G5S
Mg in 5G4A
Mg in 5G57
Mg in 5G50
Mg in 5G41
Mg in 5G3Z

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy