Chlorine in PDB 7kis: Crystal Structure of Pseudomonas Aeruginosa PBP2 in Complex with Wck 5153

All present enzymatic activity of Crystal Structure of Pseudomonas Aeruginosa PBP2 in Complex with Wck 5153:
3.4.16.4;

The structure of Crystal Structure of Pseudomonas Aeruginosa PBP2 in Complex with Wck 5153, PDB code: 7kis was solved by M.Rajavel, F.Van Den Akker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.67 / 2.87
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	82.018, 75.924, 97.299, 90, 106.73, 90
R / Rfree (%)	25.8 / 31.7

The binding sites of Chlorine atom in the Crystal Structure of Pseudomonas Aeruginosa PBP2 in Complex with Wck 5153 (pdb code 7kis). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Pseudomonas Aeruginosa PBP2 in Complex with Wck 5153, PDB code: 7kis:

Chlorine binding site 1 out of 1 in the Crystal Structure of Pseudomonas Aeruginosa PBP2 in Complex with Wck 5153


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Pseudomonas Aeruginosa PBP2 in Complex with Wck 5153 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl702 b:44.4 occ:1.00 NH2 A:ARG383 3.4 42.0 1.0 NH2 A:ARG525 3.7 31.6 1.0 NH1 A:ARG525 4.0 33.1 1.0 O A:HOH813 4.2 26.6 1.0 CZ A:ARG383 4.3 44.1 1.0 NH1 A:ARG383 4.3 37.5 1.0 CZ A:ARG525 4.3 29.9 1.0 CH2 A:TRP367 4.5 34.4 1.0

M.Rajavel, V.Kumar, H.Nguyen, J.Wyatt, S.H.Marshall, K.M.Papp-Wallace, P.Deshpande, S.Bhavsar, R.Yeole, S.Bhagwat, M.Patel, R.A.Bonomo, F.Van Den Akker. Structural Characterization of Diazabicyclooctane Beta-Lactam 'Enhancers' in Complex with Penicillin-Binding Proteins PBP2 and PBP3 of Pseudomonas Aeruginosa Mbio 2020.
ISSN: ESSN 2150-7511