Atomistry » Chlorine » PDB 7lrf-7m09 » 7lxb
Atomistry »
  Chlorine »
    PDB 7lrf-7m09 »
      7lxb »

Chlorine in PDB 7lxb: Hela-Tubulin in Complex with Cryptophycin 52

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Hela-Tubulin in Complex with Cryptophycin 52 (pdb code 7lxb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 8 binding sites of Chlorine where determined in the Hela-Tubulin in Complex with Cryptophycin 52, PDB code: 7lxb:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Chlorine binding site 1 out of 8 in 7lxb

Go back to Chlorine Binding Sites List in 7lxb
Chlorine binding site 1 out of 8 in the Hela-Tubulin in Complex with Cryptophycin 52


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Hela-Tubulin in Complex with Cryptophycin 52 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1201

b:93.2
occ:1.00
 CL1 B:YGY1201 0.0 93.2 1.0
C31 B:YGY1201 1.8 93.2 1.0
C35 B:YGY1201 2.3 93.2 1.0
C32 B:YGY1201 2.7 93.2 1.0
C30 B:YGY1201 2.8 93.2 1.0
O8 B:YGY1201 3.0 93.2 1.0
CB A:CYS347 3.4 121.0 1.0
O A:MET313 3.6 115.5 1.0
CZ3 A:TRP346 3.7 118.6 1.0
C33 B:YGY1201 4.0 93.2 1.0
SG A:CYS347 4.1 121.0 1.0
C29 B:YGY1201 4.1 93.2 1.0
CH2 A:TRP346 4.2 118.6 1.0
C A:MET313 4.3 115.5 1.0
CE3 A:TRP346 4.4 118.6 1.0
O A:PRO348 4.5 111.4 1.0
CA A:MET313 4.5 115.5 1.0
C34 B:YGY1201 4.5 93.2 1.0
CB A:MET313 4.7 115.5 1.0
CA A:CYS347 4.7 121.0 1.0
O A:CYS347 4.7 121.0 1.0
C A:CYS347 4.9 121.0 1.0

Chlorine binding site 2 out of 8 in 7lxb

Go back to Chlorine Binding Sites List in 7lxb
Chlorine binding site 2 out of 8 in the Hela-Tubulin in Complex with Cryptophycin 52


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Hela-Tubulin in Complex with Cryptophycin 52 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl1201

b:93.2
occ:1.00
 CL1 D:YGY1201 0.0 93.2 1.0
C31 D:YGY1201 1.8 93.2 1.0
C35 D:YGY1201 2.3 93.2 1.0
C32 D:YGY1201 2.7 93.2 1.0
C30 D:YGY1201 2.8 93.2 1.0
O8 D:YGY1201 3.0 93.2 1.0
CB C:CYS347 3.4 121.0 1.0
O C:MET313 3.6 115.5 1.0
CZ3 C:TRP346 3.7 118.6 1.0
C33 D:YGY1201 4.0 93.2 1.0
SG C:CYS347 4.1 121.0 1.0
C29 D:YGY1201 4.1 93.2 1.0
CH2 C:TRP346 4.2 118.6 1.0
C C:MET313 4.3 115.5 1.0
CE3 C:TRP346 4.4 118.6 1.0
O C:PRO348 4.5 111.4 1.0
CA C:MET313 4.5 115.5 1.0
C34 D:YGY1201 4.5 93.2 1.0
CB C:MET313 4.7 115.5 1.0
CA C:CYS347 4.7 121.0 1.0
O C:CYS347 4.7 121.0 1.0
C C:CYS347 4.9 121.0 1.0

Chlorine binding site 3 out of 8 in 7lxb

Go back to Chlorine Binding Sites List in 7lxb
Chlorine binding site 3 out of 8 in the Hela-Tubulin in Complex with Cryptophycin 52


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Hela-Tubulin in Complex with Cryptophycin 52 within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Cl1201

b:93.2
occ:1.00
 CL1 F:YGY1201 0.0 93.2 1.0
C31 F:YGY1201 1.8 93.2 1.0
C35 F:YGY1201 2.3 93.2 1.0
C32 F:YGY1201 2.7 93.2 1.0
C30 F:YGY1201 2.8 93.2 1.0
O8 F:YGY1201 3.0 93.2 1.0
CB E:CYS347 3.4 121.0 1.0
O E:MET313 3.6 115.5 1.0
CZ3 E:TRP346 3.7 118.6 1.0
C33 F:YGY1201 4.0 93.2 1.0
SG E:CYS347 4.1 121.0 1.0
C29 F:YGY1201 4.1 93.2 1.0
CH2 E:TRP346 4.2 118.6 1.0
C E:MET313 4.3 115.5 1.0
CE3 E:TRP346 4.4 118.6 1.0
O E:PRO348 4.5 111.4 1.0
CA E:MET313 4.5 115.5 1.0
C34 F:YGY1201 4.5 93.2 1.0
CB E:MET313 4.7 115.5 1.0
CA E:CYS347 4.7 121.0 1.0
O E:CYS347 4.7 121.0 1.0
C E:CYS347 4.9 121.0 1.0

Chlorine binding site 4 out of 8 in 7lxb

Go back to Chlorine Binding Sites List in 7lxb
Chlorine binding site 4 out of 8 in the Hela-Tubulin in Complex with Cryptophycin 52


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Hela-Tubulin in Complex with Cryptophycin 52 within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Cl1201

b:93.2
occ:1.00
 CL1 H:YGY1201 0.0 93.2 1.0
C31 H:YGY1201 1.8 93.2 1.0
C35 H:YGY1201 2.3 93.2 1.0
C32 H:YGY1201 2.7 93.2 1.0
C30 H:YGY1201 2.8 93.2 1.0
O8 H:YGY1201 3.0 93.2 1.0
CB G:CYS347 3.4 121.0 1.0
O G:MET313 3.6 115.5 1.0
CZ3 G:TRP346 3.7 118.6 1.0
C33 H:YGY1201 4.0 93.2 1.0
SG G:CYS347 4.1 121.0 1.0
C29 H:YGY1201 4.1 93.2 1.0
CH2 G:TRP346 4.2 118.6 1.0
C G:MET313 4.3 115.5 1.0
CE3 G:TRP346 4.4 118.6 1.0
O G:PRO348 4.5 111.4 1.0
CA G:MET313 4.5 115.5 1.0
C34 H:YGY1201 4.5 93.2 1.0
CB G:MET313 4.7 115.5 1.0
CA G:CYS347 4.7 121.0 1.0
O G:CYS347 4.7 121.0 1.0
C G:CYS347 4.9 121.0 1.0

Chlorine binding site 5 out of 8 in 7lxb

Go back to Chlorine Binding Sites List in 7lxb
Chlorine binding site 5 out of 8 in the Hela-Tubulin in Complex with Cryptophycin 52


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Hela-Tubulin in Complex with Cryptophycin 52 within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Cl1201

b:93.2
occ:1.00
 CL1 J:YGY1201 0.0 93.2 1.0
C31 J:YGY1201 1.8 93.2 1.0
C35 J:YGY1201 2.3 93.2 1.0
C32 J:YGY1201 2.7 93.2 1.0
C30 J:YGY1201 2.8 93.2 1.0
O8 J:YGY1201 3.0 93.2 1.0
CB I:CYS347 3.4 121.0 1.0
O I:MET313 3.6 115.5 1.0
CZ3 I:TRP346 3.7 118.6 1.0
C33 J:YGY1201 4.0 93.2 1.0
SG I:CYS347 4.1 121.0 1.0
C29 J:YGY1201 4.1 93.2 1.0
CH2 I:TRP346 4.2 118.6 1.0
C I:MET313 4.3 115.5 1.0
CE3 I:TRP346 4.4 118.6 1.0
O I:PRO348 4.5 111.4 1.0
CA I:MET313 4.5 115.5 1.0
C34 J:YGY1201 4.5 93.2 1.0
CB I:MET313 4.7 115.5 1.0
CA I:CYS347 4.7 121.0 1.0
O I:CYS347 4.7 121.0 1.0
C I:CYS347 4.9 121.0 1.0

Chlorine binding site 6 out of 8 in 7lxb

Go back to Chlorine Binding Sites List in 7lxb
Chlorine binding site 6 out of 8 in the Hela-Tubulin in Complex with Cryptophycin 52


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Hela-Tubulin in Complex with Cryptophycin 52 within 5.0Å range:
probe atom residue distance (Å) B Occ
L:Cl1201

b:93.2
occ:1.00
 CL1 L:YGY1201 0.0 93.2 1.0
C31 L:YGY1201 1.8 93.2 1.0
C35 L:YGY1201 2.3 93.2 1.0
C32 L:YGY1201 2.7 93.2 1.0
C30 L:YGY1201 2.8 93.2 1.0
O8 L:YGY1201 3.0 93.2 1.0
CB K:CYS347 3.4 121.0 1.0
O K:MET313 3.6 115.5 1.0
CZ3 K:TRP346 3.7 118.6 1.0
C33 L:YGY1201 4.0 93.2 1.0
SG K:CYS347 4.1 121.0 1.0
C29 L:YGY1201 4.1 93.2 1.0
CH2 K:TRP346 4.2 118.6 1.0
C K:MET313 4.3 115.5 1.0
CE3 K:TRP346 4.4 118.6 1.0
O K:PRO348 4.5 111.4 1.0
CA K:MET313 4.5 115.5 1.0
C34 L:YGY1201 4.5 93.2 1.0
CB K:MET313 4.7 115.5 1.0
CA K:CYS347 4.7 121.0 1.0
O K:CYS347 4.7 121.0 1.0
C K:CYS347 4.9 121.0 1.0

Chlorine binding site 7 out of 8 in 7lxb

Go back to Chlorine Binding Sites List in 7lxb
Chlorine binding site 7 out of 8 in the Hela-Tubulin in Complex with Cryptophycin 52


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Hela-Tubulin in Complex with Cryptophycin 52 within 5.0Å range:
probe atom residue distance (Å) B Occ
N:Cl1201

b:93.2
occ:1.00
 CL1 N:YGY1201 0.0 93.2 1.0
C31 N:YGY1201 1.8 93.2 1.0
C35 N:YGY1201 2.3 93.2 1.0
C32 N:YGY1201 2.7 93.2 1.0
C30 N:YGY1201 2.8 93.2 1.0
O8 N:YGY1201 3.0 93.2 1.0
CB M:CYS347 3.4 121.0 1.0
O M:MET313 3.6 115.5 1.0
CZ3 M:TRP346 3.7 118.6 1.0
C33 N:YGY1201 4.0 93.2 1.0
SG M:CYS347 4.1 121.0 1.0
C29 N:YGY1201 4.1 93.2 1.0
CH2 M:TRP346 4.2 118.6 1.0
C M:MET313 4.3 115.5 1.0
CE3 M:TRP346 4.4 118.6 1.0
O M:PRO348 4.5 111.4 1.0
CA M:MET313 4.5 115.5 1.0
C34 N:YGY1201 4.5 93.2 1.0
CB M:MET313 4.7 115.5 1.0
CA M:CYS347 4.7 121.0 1.0
O M:CYS347 4.7 121.0 1.0
C M:CYS347 4.9 121.0 1.0

Chlorine binding site 8 out of 8 in 7lxb

Go back to Chlorine Binding Sites List in 7lxb
Chlorine binding site 8 out of 8 in the Hela-Tubulin in Complex with Cryptophycin 52


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Hela-Tubulin in Complex with Cryptophycin 52 within 5.0Å range:
probe atom residue distance (Å) B Occ
P:Cl1201

b:93.2
occ:1.00
 CL1 P:YGY1201 0.0 93.2 1.0
C31 P:YGY1201 1.8 93.2 1.0
C35 P:YGY1201 2.3 93.2 1.0
C32 P:YGY1201 2.7 93.2 1.0
C30 P:YGY1201 2.8 93.2 1.0
O8 P:YGY1201 3.0 93.2 1.0
CB O:CYS347 3.4 121.0 1.0
O O:MET313 3.6 115.5 1.0
CZ3 O:TRP346 3.7 118.6 1.0
C33 P:YGY1201 4.0 93.2 1.0
SG O:CYS347 4.1 121.0 1.0
C29 P:YGY1201 4.1 93.2 1.0
CH2 O:TRP346 4.2 118.6 1.0
C O:MET313 4.3 115.5 1.0
CE3 O:TRP346 4.4 118.6 1.0
O O:PRO348 4.5 111.4 1.0
CA O:MET313 4.5 115.5 1.0
C34 P:YGY1201 4.5 93.2 1.0
CB O:MET313 4.7 115.5 1.0
CA O:CYS347 4.7 121.0 1.0
O O:CYS347 4.7 121.0 1.0
C O:CYS347 4.9 121.0 1.0

Reference:

E.Eren, N.R.Watts, D.L.Sackett, P.T.Wingfield. Conformational Changes in Tubulin Upon Binding Cryptophycin-52 Reveal Its Mechanism of Action J.Biol.Chem. 2021.
ISSN: ESSN 1083-351X
DOI: 10.1016/J.JBC.2021.101138
Page generated: Sun Jul 13 03:54:24 2025

Last articles

Mn in 9LJU
Mn in 9LJW
Mn in 9LJS
Mn in 9LJR
Mn in 9LJT
Mn in 9LJV
Mg in 9UA2
Mg in 9R96
Mg in 9VM1
Mg in 9P01
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy