Atomistry » Chlorine » PDB 7np2-7nwc » 7nt2
Atomistry »
  Chlorine »
    PDB 7np2-7nwc »
      7nt2 »

Chlorine in PDB 7nt2: Crystal Structure of Sars COV2 Main Protease in Complex with FSP006

Enzymatic activity of Crystal Structure of Sars COV2 Main Protease in Complex with FSP006

All present enzymatic activity of Crystal Structure of Sars COV2 Main Protease in Complex with FSP006:
3.4.22.69;

Protein crystallography data

The structure of Crystal Structure of Sars COV2 Main Protease in Complex with FSP006, PDB code: 7nt2 was solved by R.Oerlemans, D.Eris, M.Wang, M.Sharpe, A.Domling, M.R.Groves, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.45 / 2.15
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 68.155, 100.588, 104.726, 90, 90, 90
R / Rfree (%) 20.2 / 25.1

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Sars COV2 Main Protease in Complex with FSP006 (pdb code 7nt2). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Sars COV2 Main Protease in Complex with FSP006, PDB code: 7nt2:

Chlorine binding site 1 out of 1 in 7nt2

Go back to Chlorine Binding Sites List in 7nt2
Chlorine binding site 1 out of 1 in the Crystal Structure of Sars COV2 Main Protease in Complex with FSP006


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Sars COV2 Main Protease in Complex with FSP006 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl603

b:60.0
occ:1.00
O B:HOH778 2.8 41.3 1.0
O B:LYS5 3.3 53.8 1.0
N A:GLN127 3.5 29.9 1.0
O A:LYS5 3.5 33.4 1.0
CA A:TYR126 3.7 31.6 1.0
CG A:LYS5 3.9 47.4 1.0
CB A:TYR126 4.0 33.6 1.0
C A:TYR126 4.1 30.9 1.0
C A:LYS5 4.2 33.2 1.0
CB A:GLN127 4.3 33.6 1.0
CB A:LYS5 4.3 39.8 1.0
O A:VAL125 4.5 28.0 1.0
CA A:GLN127 4.5 33.2 1.0
C B:LYS5 4.5 46.3 1.0
N A:ALA7 4.8 26.8 1.0
N A:MET6 4.8 33.1 1.0
CA A:LYS5 4.8 38.9 1.0
N A:TYR126 4.9 30.5 1.0
O A:GLN127 5.0 33.8 1.0
CB A:ALA7 5.0 26.9 1.0

Reference:

A.Doemling, F.Sutanto, S.Shaabani, R.Oerlemans, E.Deniz, P.Patil, M.Hadian, M.Wang, M.E.Sharpe, M.R.Groves. Marriage of High Throughput Synthesis and High Throughput Protein Crystallography. Angew.Chem.Int.Ed.Engl. 2021.
ISSN: ESSN 1521-3773
PubMed: 34097796
DOI: 10.1002/ANIE.202105584
Page generated: Sun Jul 13 04:35:35 2025

Last articles

Mg in 4NXI
Mg in 4NX8
Mg in 4NV0
Mg in 4NWI
Mg in 4NX5
Mg in 4NV3
Mg in 4NW7
Mg in 4NRU
Mg in 4NST
Mg in 4NUA
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy