Atomistry » Chlorine » PDB 7ovd-7p2t » 7p2l
Atomistry »
  Chlorine »
    PDB 7ovd-7p2t »
      7p2l »

Chlorine in PDB 7p2l: Thermostabilised 7TM Domain of Human MGLU5 Receptor Bound to Photoswitchable Ligand Alloswitch-1

Enzymatic activity of Thermostabilised 7TM Domain of Human MGLU5 Receptor Bound to Photoswitchable Ligand Alloswitch-1

All present enzymatic activity of Thermostabilised 7TM Domain of Human MGLU5 Receptor Bound to Photoswitchable Ligand Alloswitch-1:
3.2.1.17;

Protein crystallography data

The structure of Thermostabilised 7TM Domain of Human MGLU5 Receptor Bound to Photoswitchable Ligand Alloswitch-1, PDB code: 7p2l was solved by C.Y.Huang, K.R.Vinothkumar, G.Lebon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 49.11 / 2.54
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 141.69, 43.4, 82.12, 90, 99.38, 90
R / Rfree (%) 22.7 / 28.5

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Thermostabilised 7TM Domain of Human MGLU5 Receptor Bound to Photoswitchable Ligand Alloswitch-1 (pdb code 7p2l). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Thermostabilised 7TM Domain of Human MGLU5 Receptor Bound to Photoswitchable Ligand Alloswitch-1, PDB code: 7p2l:

Chlorine binding site 1 out of 1 in 7p2l

Go back to Chlorine Binding Sites List in 7p2l
Chlorine binding site 1 out of 1 in the Thermostabilised 7TM Domain of Human MGLU5 Receptor Bound to Photoswitchable Ligand Alloswitch-1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Thermostabilised 7TM Domain of Human MGLU5 Receptor Bound to Photoswitchable Ligand Alloswitch-1 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1201

b:69.8
occ:1.00
CL A:4YI1201 0.0 69.8 1.0
C A:4YI1201 1.8 63.4 1.0
C1 A:4YI1201 2.7 63.6 1.0
C5 A:4YI1201 2.8 61.0 1.0
N A:4YI1201 3.0 56.7 1.0
C6 A:4YI1201 3.1 57.3 1.0
O A:TRP785 3.6 56.7 1.0
CE3 A:TRP785 3.6 56.3 1.0
C18 A:4YI1201 3.7 61.8 1.0
O1 A:4YI1201 3.7 57.1 1.0
CD1 A:LEU744 3.7 71.5 1.0
C7 A:4YI1201 3.9 53.8 1.0
C2 A:4YI1201 4.0 62.8 1.0
CD2 A:TRP785 4.1 54.2 1.0
C4 A:4YI1201 4.1 61.7 1.0
CA A:TRP785 4.1 52.9 1.0
O A:4YI1201 4.1 58.4 1.0
C17 A:4YI1201 4.2 54.4 1.0
CB A:PHE788 4.3 78.8 1.0
CZ3 A:TRP785 4.3 58.8 1.0
C A:TRP785 4.3 52.3 1.0
CB A:TRP785 4.3 53.8 1.0
CG A:TRP785 4.4 55.1 1.0
O A:PHE788 4.5 84.0 1.0
C3 A:4YI1201 4.6 66.0 1.0
C A:PHE788 4.6 76.3 1.0
CD2 A:LEU744 4.8 69.1 1.0
CG2 A:VAL789 4.9 65.9 1.0
CG A:LEU744 4.9 67.2 1.0
CA A:PHE788 4.9 77.3 1.0
N A:VAL789 4.9 74.1 1.0
CE2 A:TRP785 5.0 53.5 1.0
C8 A:4YI1201 5.0 51.9 1.0

Reference:

C.Nasrallah, G.Cannone, J.Briot, K.Rottier, E.A.Berizzi, C.Y.Huang, R.B.Quast, F.Hoh, J.L.Baneres, F.Malhaire, L.Berto, A.Dumazer, J.Font-Igles, X.Gomez-Santacana, J.Catena, J.Kniazeff, C.Goudet, A.Llebaria, J.P.Pin, K.R.Vinothkumar, G.Lebon. Agonists and Allosteric Modulators Promote Sigalling From Different Metabotropic Glutamate Receptor 5 Conformations Cell Rep 2021.
ISSN: ESSN 2211-1247
Page generated: Sun Jul 13 05:32:08 2025

Last articles

Cd in 9J00
Cd in 9J01
Ca in 9VAK
Ca in 9O9V
Ca in 9U8G
Ca in 9UD8
Ca in 9R0Q
Ca in 9QDT
Ca in 9O4Q
Ca in 9O4O
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy