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Atomistry » Chlorine » PDB 7q7n-7qhe » 7qgx » |
Chlorine in PDB 7qgx: Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic AcidEnzymatic activity of Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid
All present enzymatic activity of Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid:
4.2.1.1; Protein crystallography data
The structure of Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid, PDB code: 7qgx
was solved by
V.Paketuryte-Latve,
A.Smirnov,
E.Manakova,
S.Grazulis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7qgx:
The structure of Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid
(pdb code 7qgx). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid, PDB code: 7qgx: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 7qgxGo back to![]() ![]()
Chlorine binding site 1 out
of 2 in the Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 2 in 7qgxGo back to![]() ![]()
Chlorine binding site 2 out
of 2 in the Human Carbonic Anhydrase II in Complex with 3-((5-Chloro-4-(4- Chlorophenyl)Thiazol-2-Yl)(4-Sulfamoylphenyl)Amino)Propanoic Acid
![]() Mono view ![]() Stereo pair view
Reference:
B.Balandis,
T.Simkunas,
V.Paketuryte-Latve,
V.Michailoviene,
A.Mickeviciute,
E.Manakova,
S.Grazulis,
S.Belyakov,
V.Kairys,
V.Mickevicius,
A.Zubriene,
D.Matulis.
Beta and Gamma Amino Acid-Substituted Benzenesulfonamides As Inhibitors of Human Carbonic Anhydrases. Pharmaceuticals V. 15 2022.
Page generated: Sun Jul 13 06:19:27 2025
ISSN: ESSN 1424-8247 PubMed: 35455474 DOI: 10.3390/PH15040477 |
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