Chlorine in PDB 7sfl: Human NKCC1 State Fu-II

The binding sites of Chlorine atom in the Human NKCC1 State Fu-II (pdb code 7sfl). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human NKCC1 State Fu-II, PDB code: 7sfl:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Human NKCC1 State Fu-II


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human NKCC1 State Fu-II within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1301 b:92.8 occ:1.00 CL1 A:FUN1301 0.0 92.8 1.0 C2 A:FUN1301 1.8 92.8 1.0 C1 A:FUN1301 2.8 92.8 1.0 C3 A:FUN1301 2.8 92.8 1.0 N1 A:FUN1301 3.0 92.8 1.0 S1 A:FUN1301 3.2 92.8 1.0 O1 A:FUN1301 3.5 92.8 1.0 O A:MET794 3.6 58.7 1.0 CE1 A:TYR903 3.7 59.9 1.0 CD1 A:TYR903 4.0 59.9 1.0 C11 A:FUN1301 4.0 92.8 1.0 C4 A:FUN1301 4.0 92.8 1.0 CD2 A:LEU886 4.2 48.4 1.0 CD2 A:LEU863 4.2 61.4 1.0 CB A:MET794 4.5 58.7 1.0 C10 A:FUN1301 4.6 92.8 1.0 O2 A:FUN1301 4.6 92.8 1.0 C A:MET794 4.7 58.7 1.0 CD2 A:LEU906 4.7 55.2 1.0 CZ A:TYR903 4.8 59.9 1.0 CG A:LEU886 4.9 48.4 1.0 CD1 A:LEU863 5.0 61.4 1.0 CB A:LEU886 5.0 48.4 1.0

Chlorine binding site 2 out of 2 in the Human NKCC1 State Fu-II


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human NKCC1 State Fu-II within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1301 b:85.2 occ:1.00 CL1 B:FUN1301 0.0 85.2 1.0 C2 B:FUN1301 1.8 85.2 1.0 C3 B:FUN1301 2.8 85.2 1.0 C1 B:FUN1301 2.8 85.2 1.0 O1 B:FUN1301 3.0 85.2 1.0 S1 B:FUN1301 3.2 85.2 1.0 O B:MET794 3.3 56.0 1.0 CD2 B:LEU863 3.4 63.7 1.0 N1 B:FUN1301 3.7 85.2 1.0 CD1 B:LEU863 3.7 63.7 1.0 C11 B:FUN1301 4.0 85.2 1.0 C4 B:FUN1301 4.0 85.2 1.0 CD2 B:LEU886 4.0 38.1 1.0 CG B:LEU863 4.1 63.7 1.0 CE B:MET794 4.1 56.0 1.0 CD1 B:LEU906 4.2 57.6 1.0 C B:MET794 4.4 56.0 1.0 CB B:MET794 4.5 56.0 1.0 C10 B:FUN1301 4.6 85.2 1.0 O2 B:FUN1301 4.6 85.2 1.0 CD1 B:TYR903 4.7 62.0 1.0 CE1 B:TYR903 4.8 62.0 1.0

M.A.Moseng, C.C.Su, K.Rios, M.Cui, M.Lyu, P.Glaza, P.A.Klenotic, E.Delpire, E.W.Yu. Inhibition Mechanism of NKCC1 Involves the Carboxyl Terminus and Long-Range Conformational Coupling. Sci Adv V. 8 Q0952 2022.
ISSN: ESSN 2375-2548
PubMed: 36306358
DOI: 10.1126/SCIADV.ABQ0952