Chlorine in PDB 7vuj: Cryo-Em Structure of A Class A Orphan Gpcr

All present enzymatic activity of Cryo-Em Structure of A Class A Orphan Gpcr:
3.2.1.8;

The structure of Cryo-Em Structure of A Class A Orphan Gpcr also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Chlorine atom in the Cryo-Em Structure of A Class A Orphan Gpcr (pdb code 7vuj). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of A Class A Orphan Gpcr, PDB code: 7vuj:

Chlorine binding site 1 out of 1 in the Cryo-Em Structure of A Class A Orphan Gpcr


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of A Class A Orphan Gpcr within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl401 b:127.0 occ:1.00 CL1 R:7ZQ401 0.0 127.0 1.0 C3 R:7ZQ401 1.8 127.0 1.0 C2 R:7ZQ401 2.8 127.0 1.0 C4 R:7ZQ401 2.8 127.0 1.0 CD1 R:ILE184 3.5 129.4 1.0 CG1 R:ILE184 4.0 129.4 1.0 C1 R:7ZQ401 4.0 127.0 1.0 C5 R:7ZQ401 4.0 127.0 1.0 OH R:TYR174 4.1 131.9 1.0 CE2 R:TYR174 4.3 131.9 1.0 CG R:PRO167 4.3 120.9 1.0 CB R:PRO167 4.4 120.9 1.0 CD1 R:ILE169 4.5 130.8 1.0 C6 R:7ZQ401 4.6 127.0 1.0 CZ2 R:TRP166 4.6 122.7 1.0 ND1 R:HIS251 4.7 133.9 1.0 CZ R:TYR174 4.7 131.9 1.0 CD R:PRO167 4.9 120.9 1.0 CE1 R:HIS251 4.9 133.9 1.0 CE2 R:TRP166 4.9 122.7 1.0

Y.Zhou, H.Daver, B.Trapkov, L.Wu, M.Wu, K.Harpsoe, P.R.Gentry, K.Liu, M.Larionova, J.Liu, N.Chen, H.Brauner-Osborne, D.E.Gloriam, T.Hua, Z.J.Liu. Molecular Insights Into Ligand Recognition and G Protein Coupling of the Neuromodulatory Orphan Receptor GPR139. Cell Res. 2021.
ISSN: ISSN 1001-0602
PubMed: 34916631
DOI: 10.1038/S41422-021-00591-W