Chlorine in PDB 7vux: Complex Structure of PD1 and 609A-Fab

The structure of Complex Structure of PD1 and 609A-Fab, PDB code: 7vux was solved by H.Huang, Z.Zhu, J.Zhao, L.Jiang, H.Yang, L.Deng, X.Meng, J.Ding, S.Yang, L.Zhao, W.Xu, X.Wang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.91 / 1.64
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	56.29, 68.41, 77.31, 90, 99.44, 90
R / Rfree (%)	16 / 20.2

The structure of Complex Structure of PD1 and 609A-Fab also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Chlorine atom in the Complex Structure of PD1 and 609A-Fab (pdb code 7vux). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Complex Structure of PD1 and 609A-Fab, PDB code: 7vux:

Chlorine binding site 1 out of 1 in the Complex Structure of PD1 and 609A-Fab


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Complex Structure of PD1 and 609A-Fab within 5.0Å range: probe atom residue distance (Å) B Occ L:Cl308 b:54.7 occ:1.00 OE1 L:GLU81 3.1 22.1 1.0 O L:HOH591 3.4 24.9 1.0 CD L:GLU81 3.9 18.7 1.0 O L:HOH558 3.9 32.3 1.0 OE2 L:GLU81 4.3 20.3 1.0 CG L:GLU81 5.0 15.5 1.0

H.Huang, Z.Zhu, J.Zhao, L.Jiang, H.Yang, L.Deng, X.Meng, J.Ding, S.Yang, L.Zhao, W.Xu, X.Wang. A Strategy For the Efficient Construction of Anti-PD1-Based Bispecific Antibodies with Desired Igg-Like Properties To Be Published.