Chlorine in PDB 7xhk: High-Resolution X-Ray Cocrystal Structure of USP7 in Complex with LX04-46

All present enzymatic activity of High-Resolution X-Ray Cocrystal Structure of USP7 in Complex with LX04-46:
3.4.19.12;

The structure of High-Resolution X-Ray Cocrystal Structure of USP7 in Complex with LX04-46, PDB code: 7xhk was solved by H.B.Sun, X.A.Wen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	12.87 / 2.30
Space group	I 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	75.961, 70.856, 77.584, 90, 95.36, 90
R / Rfree (%)	22 / 26.4

The binding sites of Chlorine atom in the High-Resolution X-Ray Cocrystal Structure of USP7 in Complex with LX04-46 (pdb code 7xhk). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the High-Resolution X-Ray Cocrystal Structure of USP7 in Complex with LX04-46, PDB code: 7xhk:

Chlorine binding site 1 out of 1 in the High-Resolution X-Ray Cocrystal Structure of USP7 in Complex with LX04-46


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of High-Resolution X-Ray Cocrystal Structure of USP7 in Complex with LX04-46 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl601 b:59.0 occ:1.00 CL1 B:DVU601 0.0 59.0 1.0 C29 B:DVU601 1.8 55.5 1.0 C30 B:DVU601 2.8 54.3 1.0 C28 B:DVU601 2.9 51.0 1.0 C27 B:DVU601 3.3 52.6 1.0 C22 B:DVU601 3.4 51.5 1.0 CB B:ARG408 3.5 51.2 1.0 O B:ARG408 3.6 52.0 1.0 C B:ARG408 3.7 48.9 1.0 O10 B:DVU601 3.9 49.2 1.0 CB B:PHE409 3.9 56.4 1.0 N23 B:DVU601 3.9 51.4 1.0 N B:PHE409 4.0 50.3 1.0 CD B:LYS420 4.0 52.9 1.0 CG B:LYS420 4.0 51.4 1.0 CE B:LYS420 4.0 52.6 1.0 CA B:PHE409 4.2 54.6 1.0 CA B:ARG408 4.2 48.4 1.0 C31 B:DVU601 4.3 56.0 1.0 C33 B:DVU601 4.3 53.0 1.0 CG B:PHE409 4.5 57.0 1.0 CB B:LYS420 4.6 53.1 1.0 CD2 B:PHE409 4.7 59.1 1.0 C21 B:DVU601 4.8 49.5 1.0 CG B:ARG408 4.8 50.5 1.0 C32 B:DVU601 4.9 55.7 1.0 C24 B:DVU601 4.9 46.4 1.0 CA B:LYS420 4.9 54.8 1.0 N B:ARG408 5.0 50.0 1.0 CB B:TYR514 5.0 42.2 1.0 CD B:ARG408 5.0 45.1 1.0

X.A.Wen, H.B.Sun, X.A.Wen. N/A N/A.