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Atomistry » Chlorine » PDB 7zga-7zsm » 7zik » |
Chlorine in PDB 7zik: Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor LP533401Enzymatic activity of Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor LP533401
All present enzymatic activity of Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor LP533401:
1.14.16.4; Protein crystallography data
The structure of Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor LP533401, PDB code: 7zik
was solved by
A.Schuetz,
U.Heinemann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7zik:
The structure of Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor LP533401 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor LP533401
(pdb code 7zik). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor LP533401, PDB code: 7zik: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 7zikGo back to![]() ![]()
Chlorine binding site 1 out
of 2 in the Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor LP533401
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 2 in 7zikGo back to![]() ![]()
Chlorine binding site 2 out
of 2 in the Crystal Structure of Human Tryptophan Hydroxylase 1 in Complex with Inhibitor LP533401
![]() Mono view ![]() Stereo pair view
Reference:
E.Specker,
S.Matthes,
R.Wesolowski,
A.Schutz,
M.Grohmann,
N.Alenina,
D.Pleimes,
K.Mallow,
M.Neuenschwander,
A.Gogolin,
M.Weise,
J.Pfeifer,
N.Ziebart,
U.Heinemann,
J.P.Von Kries,
M.Nazare,
M.Bader.
Structure-Based Design of Xanthine-Benzimidazole Derivatives As Novel and Potent Tryptophan Hydroxylase Inhibitors. J.Med.Chem. V. 65 11126 2022.
Page generated: Sun Jul 13 08:47:52 2025
ISSN: ISSN 0022-2623 PubMed: 35921615 DOI: 10.1021/ACS.JMEDCHEM.2C00598 |
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