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Atomistry » Chlorine » PDB 7zga-7zsm » 7zkx | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 7zga-7zsm » 7zkx » |
Chlorine in PDB 7zkx: SRPK2 in Complex with InhibitorEnzymatic activity of SRPK2 in Complex with Inhibitor
All present enzymatic activity of SRPK2 in Complex with Inhibitor:
2.7.11.1; Protein crystallography data
The structure of SRPK2 in Complex with Inhibitor, PDB code: 7zkx
was solved by
U.Graedler,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7zkx:
The structure of SRPK2 in Complex with Inhibitor also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the SRPK2 in Complex with Inhibitor
(pdb code 7zkx). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the SRPK2 in Complex with Inhibitor, PDB code: 7zkx: Chlorine binding site 1 out of 1 in 7zkxGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the SRPK2 in Complex with Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
M.Schroder,
M.Leiendecker,
U.Gradler,
J.Braun,
A.Blum,
M.Wanior,
B.T.Berger,
A.Kramer,
S.Muller,
C.Esdar,
S.Knapp,
T.Heinrich.
Msc-1186, A Highly Selective Pan-Srpk Inhibitor Based on An Exceptionally Decorated Benzimidazole-Pyrimidine Core. J.Med.Chem. V. 66 837 2023.
Page generated: Sun Jul 13 08:48:33 2025
ISSN: ISSN 0022-2623 PubMed: 36516476 DOI: 10.1021/ACS.JMEDCHEM.2C01705 |
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