Atomistry » Chlorine » PDB 8ay9-8b6t » 8b4w
Atomistry »
  Chlorine »
    PDB 8ay9-8b6t »
      8b4w »

Chlorine in PDB 8b4w: X-Ray Structure of Furin (PCSK3) in Complex with 1H-Isoindol-3-Amine

Enzymatic activity of X-Ray Structure of Furin (PCSK3) in Complex with 1H-Isoindol-3-Amine

All present enzymatic activity of X-Ray Structure of Furin (PCSK3) in Complex with 1H-Isoindol-3-Amine:
3.4.21.75;

Protein crystallography data

The structure of X-Ray Structure of Furin (PCSK3) in Complex with 1H-Isoindol-3-Amine, PDB code: 8b4w was solved by S.O.Dahms, H.Brandstetter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.03 / 1.60
Space group P 65 2 2
Cell size a, b, c (Å), α, β, γ (°) 131.959, 131.959, 155.34, 90, 90, 120
R / Rfree (%) 16.6 / 17.9

Other elements in 8b4w:

The structure of X-Ray Structure of Furin (PCSK3) in Complex with 1H-Isoindol-3-Amine also contains other interesting chemical elements:

Sodium (Na) 4 atoms
Calcium (Ca) 3 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the X-Ray Structure of Furin (PCSK3) in Complex with 1H-Isoindol-3-Amine (pdb code 8b4w). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the X-Ray Structure of Furin (PCSK3) in Complex with 1H-Isoindol-3-Amine, PDB code: 8b4w:

Chlorine binding site 1 out of 1 in 8b4w

Go back to Chlorine Binding Sites List in 8b4w
Chlorine binding site 1 out of 1 in the X-Ray Structure of Furin (PCSK3) in Complex with 1H-Isoindol-3-Amine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of X-Ray Structure of Furin (PCSK3) in Complex with 1H-Isoindol-3-Amine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl611

b:20.6
occ:1.00
HZ1 A:LYS449 2.3 23.4 1.0
HH A:TYR571 2.4 23.9 1.0
HD2 A:LYS449 3.1 24.1 1.0
HE1 A:TYR571 3.1 21.6 1.0
OH A:TYR571 3.1 19.9 1.0
NZ A:LYS449 3.2 19.5 1.0
O A:HOH871 3.4 28.0 1.0
HZ3 A:LYS449 3.6 23.4 1.0
HH A:TYR313 3.6 30.3 1.0
HZ A:PHE275 3.6 26.5 0.0
HE3 A:LYS449 3.6 22.6 1.0
HZ2 A:LYS449 3.7 23.4 1.0
OH A:TYR313 3.8 25.2 1.0
HE2 A:PHE275 3.8 25.9 0.0
CE A:LYS449 3.8 18.8 1.0
CE1 A:TYR571 3.8 18.0 1.0
CD A:LYS449 3.8 20.1 1.0
CZ A:TYR571 3.9 19.1 1.0
CZ A:PHE275 4.1 22.0 0.0
CE2 A:PHE275 4.2 21.5 0.0
HH22 A:ARG490 4.3 23.2 1.0
HD3 A:LYS449 4.3 24.1 1.0
O A:HOH1021 4.5 21.6 1.0
HE2 A:LYS449 4.7 22.6 1.0
HG3 A:LYS449 4.9 21.7 1.0
CG A:LYS449 5.0 18.1 1.0
HB2 A:LYS449 5.0 24.7 1.0

Reference:

S.O.Dahms, H.Brandstetter. Aminoisoindol-Based Furin Inhibitors To Be Published.
Page generated: Sun Jul 13 09:25:30 2025

Last articles

Mn in 9LJU
Mn in 9LJW
Mn in 9LJS
Mn in 9LJR
Mn in 9LJT
Mn in 9LJV
Mg in 9UA2
Mg in 9R96
Mg in 9VM1
Mg in 9P01
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy